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Merck

SAB4503779

Sigma-Aldrich

Anti-phospho-Smad1 (pSer465) antibody produced in rabbit

affinity isolated antibody

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 52 kDa

物種活性

mouse, rat, human

濃度

~1 mg/mL

技術

ELISA: 1:20000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

phosphorylation (pSer465)

基因資訊

human ... SMAD1(4086)

一般說明

Smad1 (SMAD family member 1) is a transcriptional activator, that is located on human chromosome 4q31.

免疫原

The antiserum was produced against synthesized peptide derived from human Smad1 around the phosphorylation site of Ser465.

Immunogen Range: 416-465

生化/生理作用

SMAD (homologues of the Drosophila protein, mothers against decapentaplegic (Mad) and the Caenorhabditis elegans protein Sma) proteins have a major role in disease development and hence act as biologic prognostic factors in diseases. miR-345 represses the multiplication, invasion and migration of prostate cancer by downregulating Smad1.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

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在文件库中查找您最近购买产品的文档。

访问文档库

The distribution and potential prognostic value of SMAD protein expression in chronic lymphocytic leukemia.
Witkowska M, et al.
Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine, 39(3), 1010428317694551-1010428317694551 (2017)
An interstitial 4q31.21q31.22 microdeletion associated with developmental delay: case report and literature review
Vlaikou AM, et al.
Cytogenetic and genome research, 142(4), 227-238 (2014)
Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal
Fuentealba LC, et al.
Cell, 131(5), 980-993 (2007)
MiR-345 suppresses proliferation, migration and invasion by targeting Smad1 in human prostate cancer
Chen QG, et al.
Journal of Cancer Research and Clinical Oncology, 142(1), 213-224 (2016)

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