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Key Documents

SAB4502043

Sigma-Aldrich

Anti-OPRD1 antibody produced in rabbit

affinity isolated antibody

别名:

δ-opioid receptor, δ-type opioid receptor, K56, MSL-2, OPRD

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 40 kDa

物種活性

human

濃度

~1 mg/mL

技術

ELISA: 1:5000
western blot: 1:500-1:1000

NCBI登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... OPRD(4985)

一般說明

Anti-OPRD1 antibody detects endogenous levels of total OPRD1 protein.
The OPRD1 (opioid receptor δ1) gene is mapped to human chromosome 1p35.3 and encodes for a G-protein-coupled receptor. It is abundantly expressed in peripheral tissues.

免疫原

The antiserum was produced against synthesized peptide derived from human OPRD1.

Immunogen Range: 311-360

生化/生理作用

OPRD1 (opioid receptor δ1) is associated with cognitive function and mood driven behavior. Anxiolytic and antidepressant actions are brought about when specific agonists bind to the OPRD1 gene. δ-opioid receptor (DOR) is known to be involved in the progression and development of specific tumours (malignant). Upregulation of this gene is observed in breast cancer, and thus, it can serve as an important therapeutic marker.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Louis Gendron et al.
Pharmacological reviews, 68(3), 631-700 (2016-06-28)
Opioids are among the most effective analgesics available and are the first choice in the treatment of acute severe pain. However, partial efficacy, a tendency to produce tolerance, and a host of ill-tolerated side effects make clinically available opioids less
Ann M Manzardo et al.
Gene, 560(2), 184-194 (2015-02-07)
Alcoholism arises from combined effects of multiple biological factors including genetic and non-genetic causes with gene/environmental interaction. Intensive research and advanced genetic technology has generated a long list of genes and biomarkers involved in alcoholism neuropathology. These markers reflect complex
Yang-Chao Wei et al.
Oncology reports, 36(5), 2579-2586 (2016-10-26)
δ‑opioid receptor (DOR) belongs to the family of G protein‑coupled receptors (GPCRs). Numerous studies have shown that DOR is widely distributed in human peripheral tissues and is closely related to the development and progression of certain malignant tumours. However, there is controversy in
Huihui Ji et al.
PloS one, 12(3), e0172335-e0172335 (2017-03-03)
Aberrant DNA methylation has been observed in the patients with Alzheimer's disease (AD), a common neurodegenerative disorder in the elderly. OPRD1 encodes the delta opioid receptor, a member of the opioid family of G-protein-coupled receptors. In the current study, we

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