SAB4300572
Anti-TRPC6 antibody produced in rabbit
affinity isolated antibody
别名:
Anti-FLJ11098 antibody produced in rabbit, Anti-FLJ14863 antibody produced in rabbit, Anti-FSGS2 antibody produced in rabbit, Anti-TRP6 antibody produced in rabbit, Anti-transient receptor potential cation channel, subfamily C, member 6 antibody produced in rabbit
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About This Item
推荐产品
生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
~100 kDa
物種活性
human, mouse, rat
濃度
1 mg/mL
技術
western blot: 1:500-1:1000
同型
IgG
免疫原序列
(Q-D-Y-L-L)
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... TRPC6(7225)
免疫原
peptide Corresponding to the amino terminal sequence from mouse TRPC6 protein , according to the protein TRPC6.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
標靶描述
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).
外觀
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Natalie Youssef et al.
Biomedicines, 9(10) (2021-10-24)
Diabetic kidney disease (DKD), a serious diabetic complication, results in podocyte loss and proteinuria through NADPH oxidases (NOX)-mediated ROS production. DUOX1 and 2 are NOX enzymes that require calcium for their activation which enters renal cells through the pivotal TRPC
Jun Wu et al.
Journal of Huntington's disease, 7(1), 35-50 (2018-02-27)
Huntington disease (HD) is a dominantly inherited neurodegenerative disorder caused by a CAG repeat expansion in the huntingtin gene. We previously discovered that mutant Huntingtin sensitizes type 1 inositol 1,4,5-trisphosphate receptor (InsP3R1) to InsP3. This causes calcium leakage from the
Hua Zhang et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 36(47), 11837-11850 (2016-11-25)
Mushroom dendritic spine structures are essential for memory storage and the loss of mushroom spines may explain memory defects in aging and Alzheimer's disease (AD). The stability of mushroom spines depends on stromal interaction molecule 2 (STIM2)-mediated neuronal-store-operated Ca2+ influx
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