SAB4200808

抗 肌球蛋白轻链激酶抗体，小鼠单克隆

clone K36, purified from hybridoma cell culture

• 别名: Kinase-related protein (KRP), MLCK, Myosin light chain kinase, Smooth muscle, Telokin, smMLCK
• 分類程式碼代碼: 12352203
• NACRES: NA.41

属性

• 生物源: mouse
• 抗體表格: purified from hybridoma cell culture
• 抗體產品種類: primary antibodies
• 無性繁殖: K36, monoclonal
• 形狀: buffered aqueous solution
• 分子量: ~160 kDa
• 物種活性: bovine, human, mouse, chicken, pig, turkey
• 包裝: antibody small pack of 25 μL
• 濃度: ~1 mg/mL
• 技術: immunoblotting: 0.25-0.5 μg/mL using chicken gizzard extract
• 同型: IgG2b
• UniProt登錄號: Q15746
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified

说明

一般說明

Myosin Light Chain Kinase (MLCK) also known as MYLK is a Ca2+/calmodulin dependent myosin light chain phosphorylating agent. This enzyme plays a major role in the phosphorylation of the regulatory light chains of myosin which are essential for the shortening and tension development of smooth muscle cells resulting in smooth muscle contraction. Myosin light chain kinase are widely expressed in many different tissues and cells of eukaryote species. There are two genes mylk1 and mylk2 encoding the MLCK protein, mylk2 is exclusively expressed in skeletal muscle cells.

免疫原

Purified chicken gizzard myosin light chain kinase.

應用

Monoclonal Anti-Myosin Light Chain Kinase recognizes the myosin light chain kinase of smooth muscle and from non-muscle cells such as cultured fibroblasts. Reactivity has been observed with myosin light chain kinase from chicken, turkey, bovine, human, mouseand pig origin. The antibody is recommended to use in various immunological techniques, including Immunoblotting (~160kDa), Immunohistochemistry and immunofluorescence.

外觀

Supplied as a solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide as a preservative.

其他說明

This product is for R&D use only, not for drug, household, or other uses.

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable