推荐产品
生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
物種活性
rat, mouse, human
技術
immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... PTK7(5754)
一般說明
Protein tyrosine kinase-7 (PTK7) is a transmembrane receptor, that belongs to the receptor protein tyrosine kinase (RTKs) family. It has an extracellular immunoglobulin-like domain, a transmembrane domain and an inert tyrosine kinase-like domain. PTK7 is located on human chromosome 6p21.
免疫原
PTK7 antibody was raised against a 18 amino acid peptide from near the carboxy terminus of human PTK7.
應用
Anti-PTK7 antibody has been used in immunohistochemistry.
生化／生理作用
Protein tyrosine kinase-7 (PTK7) stimulates cell proliferation and invasion. It plays a vital role embryonic development and disease. PTK7 controls radioresistance with the help of nuclear factor-κ B in esophageal squamous cell carcinoma.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
聯結
The action of this antibody can be blocked using blocking peptide SBP3500340.
外觀
Supplied in PBS with 0.02% sodium azide.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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相關產品
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Ron Chen et al.
Cancer research, 74(10), 2892-2902 (2014-03-22)
Lung cancer remains the most common cause of cancer-related death worldwide and it continues to lack effective treatment. The increasingly large and diverse public databases of lung cancer gene expression constitute a rich source of candidate oncogenic drivers and therapeutic
PTK7 regulates radioresistance through nuclear factor-kappa B in esophageal squamous cell carcinoma.
Park M, et al.
Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine, 37(10), 14217-14224 (2016)
PTK7 overexpression in colorectal tumors: Clinicopathological correlation and prognosis relevance.
Tian X, et al.
Oncology Reports, 36(4), 1829-1836 (2016)
Undetectable and Decreased Expression of KIAA1949 (Phostensin) Encoded on Chromosome 6p21.33 in Human Breast Cancers Revealed by Transcriptome Analysis
Su YA, et al.
Journal of Cancer, 1, 38-50 (2010)
Xiuyun Tian et al.
Oncology reports, 36(4), 1829-1836 (2016-08-09)
Colorectal cancer (CRC) has one of the highest mortality rates in the worldwide and its incidence has been increasing in recent years. Protein tyrosine kinase-7 (PTK7) is an inactive member of receptor protein tyrosine kinase (RPTK)-like molecules, which is involved
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