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Merck
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Key Documents

SAB1300688

Sigma-Aldrich

Anti-LIN28A (N-term) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

别名:

Anti-CSDD1, Anti-LIN28, Anti-LIN28A, Anti-Lin-28 homolog A, Anti-Zinc finger CCHC domain-containing protein 1

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.43

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

human

技術

immunohistochemistry: 1:50-1:100
indirect ELISA: 1:1000

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... LIN28A(79727)

一般說明

LIN28A acts as a ′translational enhancer′, driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. Binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. It is essential for skeletal muscle differentiation through the translational up-regulation of IGF2 expression.

免疫原

LIN28A (NP_078950, 15-49)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human LIN28A.

外觀

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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