S9132

螺旋霉素

• 别名: Rovamycin, Formacidine
• CAS号: 8025-81-8
• EC號碼: 232-429-6
• MDL號碼: MFCD01314545
• 分類程式碼代碼: 51283208
• PubChem物質ID: 24899826
• NACRES: NA.85

属性

• 形狀: powder
• 品質等級: 200
• 光學活性: [α]/D -85 to -80° in water (Specific rotation (dry basis))
• 效力: ≥4100 I.U. per mg (dry basis)
• 儲存條件: (Keep container tightly closed in a dry and well-ventilated place.)
• 顏色: white to light yellow
• 溶解度: methanol: soluble
• 正離子痕跡: heavy metals: ≤20 ppm
• 抗生素活性譜: Gram-positive bacteria
• 作用方式: protein synthesis | interferes
• 儲存溫度: 2-8°C
• SMILES 字串: CO[C@H]1[C@H](O)CC(=O)O[C@H](C)C\C=C\C=C\[C@H](OC2CCC(C(C)O2)N(C)C)[C@H](C)C[C@H](CC=O)[C@@H]1OC3OC(C)C(OC4CC(C)(O)C(O)C(C)O4)C(C3O)N(C)C
• InChI: 1S/C43H74N2O14/c1-24-21-29(19-20-46)39(59-42-37(49)36(45(9)10)38(27(4)56-42)58-35-23-43(6,51)41(50)28(5)55-35)40(52-11)31(47)22-33(48)53-25(2)15-13-12-14-16-32(24)57-34-18-17-30(44(7)8)26(3)54-34/h12-14,16,20,24-32,34-42,47,49-51H,15,17-19,21-23H2,1-11H3/b13-12+,16-14+/t24-,25-,26?,27?,28?,29+,30?,31-,32+,34?,35?,36?,37?,38?,39+,40+,41?,42?,43?/m1/s1
• InChI 密鑰: ACTOXUHEUCPTEW-JMRHEKERSA-N

说明

一般說明

Chemical structure: macrolide

應用

Spiramycin is a macrolide antibiotic that is commonly used to treat infections of soft tissues. It has been used to treat bronchopulmonary infections in adults and has been used to study septicemia in mice .

生化／生理作用

Spiramycin is a 16-membered ring macrolide antibiotic from Streptomyces ambofaciens. It inhibits bacterial protein synthesis at the level of peptidy-tRNA dissociation from ribosomes. It is mainly used against Gram-positive bacteria.

品質

A mixture of Spiramycin I, II and III.

其他說明

Keep container tightly closed in a dry and well-ventilated place.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)