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Merck

T3397

Sigma-Aldrich

泰乐菌素 溶液

solution, suitable for cell culture, BioReagent

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About This Item

CAS号:
MDL编号:
UNSPSC代码:
12352207
PubChem化学物质编号:
NACRES:
NA.76

产品名称

泰乐菌素 溶液, 8 mg/mL in 0.9% NaCl, 0.1 μm filtered, BioReagent, suitable for cell culture

质量水平

无菌性

0.1 μm filtered

产品线

BioReagent

表单

solution

浓度

8 mg/mL in 0.9% NaCl

技术

cell culture | mammalian: suitable

杂质

endotoxin, tested

颜色

colorless to yellow

抗生素抗菌谱

Gram-positive bacteria
mycoplasma

作用机制

protein synthesis | interferes

储存温度

2-8°C

SMILES字符串

O[C@H]([C@@H](O)C(O)=O)C(O)=O.CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(O)[C@@H](O)[C@H](C)O3)[C@@H]([C@H]2O)N(C)C)[C@@H](CC=O)C[C@@H](C)C(=O)\C=C\C(C)=C\[C@@H]1CO[C@@H]4O[C@H](C)[C@@H](O)[C@@H](OC)[C@H]4OC

InChI

1S/C46H77NO17.C4H6O6/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35;5-1(3(7)8)2(6)4(9)10/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3;1-2,5-6H,(H,7,8)(H,9,10)/b15-14+,23-18+;/t24-,25+,26-,27-,28+,29+,30-,32-,33-,35+,36-,37-,38-,39-,40-,41-,42-,43+,44+,45-,46-;1-,2-/m11/s1

InChI key

ICVKYYINQHWDLM-KBEWXLTPSA-N

一般描述

Chemical structure: macrolide
Tylosin is a macrolide antibiotic, which comprises of a 16-member lactone ring. This solution is recommended for use at 1 mL/L.

应用

Tylosin solution has been used as an antimicrobial agent in antibiotic susceptibility minimal inhibitory concentration(MIC) of E. coli and S. aureus isolates. It has also been used as a component of Dulbecco′s modified Eagle′s (DMEM) medium for self-inactivating lentivirus production and skin fibroblast cultivation.

生化/生理作用

Tylosin inhibits bacterial protein synthesis by binding to the large subunit 50S. It is effective against Gram-positive bacteria and mycoplasma and is used in veterinary medicine. It has been used to study implant site abscess prevention in cattle and Mycoplasma gallisepticum and Mycoplasma meleagridis infections.

包装

20ML

制备说明

This product was formulated to contain 8 mg/ml tylosin in 0.9% sodium chloride.

储存及稳定性

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and keep upright to prevent leakage.

其他说明

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Frizzled 1 and Wnt1 as new potential therapeutic targets in the traumatically injured spinal cord
Gonzalez P, et al.
Cellular and Molecular Life Sciences, 80, 1-32 (2020)
Cytosolic, but not matrix, calcium is essential for adjustment of mitochondrial pyruvate supply
Szibor M, et al.
Test, 295(14), 4383-4397 (2020)
Tools for characterizing bacterial protein synthesis inhibitors
Orelle C, et al.
Antimicrobial Agents and Chemotherapy, 57(12), 5994-6004 (2013)
Bei Liu et al.
Journal of hazardous materials, 325, 129-135 (2016-12-09)
In order to be more practical on evaluating the response of soil microbial communities to Cu contamination, we compared the microbial activity and selection for the microbial tolerance after a high level Cu exposure in single and corresponding repeated addition.
Effects of a tylosin tartrate pellet added to cattle growth implants on the incidence of implant site abscesses
Zollers JrWG, et al.
The Protein Kinase Facts Book, 18(3), 258-261 (2002)

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