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Merck
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文件

S0942

Sigma-Aldrich

磷酸酶底物

chromogenic, tablet (round)

别名:

4-硝基苯磷酸盐 二钠盐 六水合物, pNPP 二钠盐 六水合物

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About This Item

线性分子式:
O2NC6H4OP(O)(ONa)2 · 6H2O
CAS号:
333338-18-4
分子量:
371.14
EC號碼:
224-246-5
MDL號碼:
MFCD00066288
分類程式碼代碼:
12352204
PubChem物質ID:
24899454
NACRES:
NA.54

product name

磷酸酶底物, 5 mg tablets

形狀

tablet (round)

儲存溫度

−20°C

SMILES 字串

O.O.O.O.O.O.[Na+].[Na+].[O-][N+](=O)c1ccc(OP([O-])([O-])=O)cc1

InChI

1S/C6H6NO6P.2Na.6H2O/c8-7(9)5-1-3-6(4-2-5)13-14(10,11)12;;;;;;;;/h1-4H,(H2,10,11,12);;;6*1H2/q;2*+1;;;;;;/p-2

InChI 密鑰

KAKKHKRHCKCAGH-UHFFFAOYSA-L

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相关类别

應用

用于碱性和酸性磷酸酶ELISA法的发色底物。产生可溶性终产物，黄色，分光光度法在405nm处读取。pNPP反应能被3N NAOH终止，在405nm处读取。

其他說明

酸性和碱性磷酸酶实验底物。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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Claire C Baniel et al.
Journal for immunotherapy of cancer, 8(2) (2020-10-30)
Some patients with cancer treated with anticancer monoclonal antibodies (mAbs) develop antidrug antibodies (ADAs) that recognize and bind the therapeutic antibody. This response may neutralize the therapeutic mAb, interfere with mAb effector function or cause toxicities. We investigated the potential
Thomas F Rogers et al.
Science (New York, N.Y.), 369(6506), 956-963 (2020-06-17)
Countermeasures to prevent and treat coronavirus disease 2019 (COVID-19) are a global health priority. We enrolled a cohort of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-recovered participants, developed neutralization assays to investigate antibody responses, adapted our high-throughput antibody generation pipeline
Yeon-Suk Yang et al.
Molecular therapy. Methods & clinical development, 17, 922-935 (2020-05-15)
Improper activity of bone-resorbing osteoclasts results in low bone density and deterioration of bone structure, which increase the risk of fractures. Anti-resorptive therapies targeting osteoclasts have proven effective in preserving bone mass, but these therapeutic agents lead to defective new
Lijun Wang et al.
Nature communications, 11(1), 282-282 (2020-01-17)
Wolff's law and the Utah Paradigm of skeletal physiology state that bone architecture adapts to mechanical loads. These models predict the existence of a mechanostat that links strain induced by mechanical forces to skeletal remodeling. However, how the mechanostat influences
Christina Papista et al.
Kidney international, 88(2), 276-285 (2015-03-26)
IgA1 complexes containing deglycosylated IgA1, IgG autoantibodies, and a soluble form of the IgA receptor (sCD89), are hallmarks of IgA nephropathy (IgAN). Food antigens, notably gluten, are associated with increased mucosal response and IgAN onset, but their implication in the
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