Q1250

奎宁 半硫酸盐 一水合物

synthetic, ≥90% (HPLC)

• 别名: Quinine sulfate (2:1) (salt) dihydrate
• 经验公式（希尔记法）: C₂₀H₂₄N₂O₂ · 0.5H₂O₄S · H₂O
• CAS号: 207671-44-1
• 分子量: 391.47
• Beilstein: 6113937
• MDL號碼: MFCD00150790
• 分類程式碼代碼: 12352210
• PubChem物質ID: 57654578
• NACRES: NA.77

属性

• 生物源: synthetic
• 品質等級: 200
• 化驗: ≥90% (HPLC)
• mp: ~225 °C (dec.) (lit.)
• 溶解度: H₂O: slightly soluble 1.2 mg/mL; ethanol: 8 mg/mL
• 抗生素活性譜: parasites
• 作用方式: enzyme | inhibits
• 起源: Bayer
• SMILES 字串: O.O.OS(O)(=O)=O.COc1ccc2nccc([C@@H](O)C3CC4CCN3C[C@@H]4C=C)c2c1.COc5ccc6nccc([C@@H](O)C7CC8CCN7C[C@@H]8C=C)c6c5
• InChI: 1S/2C20H24N2O2.H2O4S.2H2O/c2*1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;1-5(2,3)4;;/h2*3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;(H2,1,2,3,4);2*1H2/t2*13-,14-,19-,20+;;;/m00.../s1
• InChI 密鑰: ZHNFLHYOFXQIOW-LPYZJUEESA-N

说明

應用

Quinine hemisulfate salt monohydrate has been used as a stimuli to evaluate its influence on sensory and cognitive factors.

生化／生理作用

钾通道阻滞剂。抗疟疾、抗胆碱能、抗高血压和降血糖剂；最初从南美树木的金鸡纳科中分离出来的生物碱。

Quinine has analgesic property.

特點和優勢

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves