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Merck
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PLA0127

Sigma-Aldrich

Rabbit anti-RNA Polymerase II Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

别名:

220kDa, DNA-directed RNA polymerase II largest subunit, DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase III largest subunit, POLR2, POLRA, RNA polymerase II 220 kd subunit, RNA polymerase II subunit B1, RNA-directed RNA polymerase II subunit RPB1, RPB1, RPBh1, RPO2, RPOL2, RpIILS, hRPB220, hsRPB1, polymerase (RNA) II (DNA directed) polypeptide A

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

100

抗體表格

affinity purified immunoglobulin

抗體產品種類

primary antibodies

等級

Powered by Bethyl Laboratories, Inc.

物種活性

human, mouse

技術

immunoprecipitation (IP): 1-4 μg/mg
western blot: 1:1,000- 1:10,000

登錄號

NP_000928.1

運輸包裝

wet ice

儲存溫度

2-8°C

目標翻譯後修改

unmodified

基因資訊

human ... RNA Polymerase II(5430)

免疫原

The epitope recognized by PLA0127 maps to the C-terminal repeat of human RNA Polymerase II (GeneID 5430).

外觀

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

其他說明

The RNA polymerase II subunit B1 (RPB1) is the largest subunit of the RNA polymerase II core complex. RNA polymerase II holoenzyme functions to transcribe DNA into messenger RNA in eukaryotes. RPB1 forms the DNA binding domain of the polymerase that forms a cleft that grabs the incoming DNA template to translocate the holoenzyme across the RNA-DNA hybrid.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類（WGK）

nwg

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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Anirban Chakraborty et al.
The Journal of biological chemistry, 299(3), 102991-102991 (2023-02-10)
A growing body of evidence indicates that RNA plays a critical role in orchestrating DNA double-strand break repair (DSBR). Recently, we showed that homologous nascent RNA can be used as a template for error-free repair of double-strand breaks (DSBs) in
Y Xu et al.
Oncogene, 36(8), 1157-1166 (2016-08-16)
The heterogeneous breast cancers can be classified into different subtypes according to their histopathological characteristics and molecular signatures. Foxa1 expression is linked with luminal breast cancer (LBC) with good prognosis, whereas Twist1 expression is associated with basal-like breast cancer (BLBC)
Zhenhua Liu et al.
Journal of cellular and molecular medicine, 22(9), 4161-4170 (2018-07-06)
Oestrogen receptor ɑ (ERɑ) is overexpressed in two-thirds of all breast cancers and involves in development and breast cancer progression. Although ERɑ-positive breast cancer could be effective treated by endocrine therapy, the endocrine resistance is still an urgent clinical problem.
Yanchang Liu et al.
Frontiers in bioengineering and biotechnology, 9, 735949-735949 (2021-12-07)
Bone marrow mesenchymal stem cells (BMSCs) play a critical role in bone formation and are extremely sensitive to external mechanical stimuli. Mechanical signals can regulate the biological behavior of cells on the surface of titanium-related prostheses and inducing osteogenic differentiation

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