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Merck
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P4194

Sigma-Aldrich

DL-苏式-1-苯基-2-棕榈酰氨基-3-吗啉-1-丙醇

98%

别名:

(±)-PPMP

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About This Item

经验公式（希尔记法）:
C29H50N2O3 · HCl
CAS号:
149022-18-4
分子量:
511.18
MDL號碼:
MFCD00211157
分類程式碼代碼:
12352211
PubChem物質ID:
24898512
NACRES:
NA.25

品質等級

100

化驗

98%

形狀

powder

脂質類型

phosphoglycerides

儲存溫度

2-8°C

SMILES 字串

CCCCCCCCCCCCCCCC(=O)N[C@H](CN1CCOCC1)[C@H](O)c2ccccc2

InChI

1S/C29H50N2O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-17-20-28(32)30-27(25-31-21-23-34-24-22-31)29(33)26-18-15-14-16-19-26/h14-16,18-19,27,29,33H,2-13,17,20-25H2,1H3,(H,30,32)/t27-,29-/m1/s1

InChI 密鑰

OFBANDBMHLEMFA-XRKRLSELSA-N

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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D Johansson et al.
British journal of cancer, 102(2), 383-391 (2009-12-17)
A major problem with cisplatin treatment is the development of acquired-drug resistance of the tumour cells. Verotoxin-1 (VT-1) exerts its cytotoxicity by targeting the membrane glycolipid globotriasosylceramide (Gb3), a molecule associated with drug resistance. Cisplatin- and VT-1-induced apoptosis involves mitogen-activated
A Abe et al.
Journal of biochemistry, 111(2), 191-196 (1992-02-01)
An inhibitor of glucosylceramide (GlcCer) synthase, 1-phenyl-2-decanoylamino-3-morpholino-1-propanol (PDMP), has been reported to deplete cells and mice of their glucosphingolipids. This inhibitor has proved useful for the elucidation of the many functions of this lipid family [reviewed by Radin, N.S. &
Virginia Sara Grancieri do Amaral et al.
International journal of molecular sciences, 21(8) (2020-04-16)
Psd1 is a pea plant defensin which can be actively expressed in Pichia pastoris and shows broad antifungal activity. This activity is dependent on fungal membrane glucosylceramide (GlcCer), which is also important for its internalization, nuclear localization, and endoreduplication. Certain
Takuya Honda et al.
Biochimica et biophysica acta. Molecular and cell biology of lipids, 1866(1), 158817-158817 (2020-09-28)
Sphingolipids represent a family of cellular lipid-molecules that regulate physiological and pathophysiological processes. Glucosylceramide (GlcCer), the simplest glycosphingolipid (GSL), is synthesized from ceramide and UDP-glucose by GlcCer synthase (GCS). Both GlcCer (and resulting GSLs) and ceramide regulate various cellular functions
Tomasz B Owczarek et al.
PloS one, 8(12), e84191-e84191 (2014-01-07)
It was recently proposed that UDP-galactose:ceramide galactosyltransferase (UGT8), enzyme responsible for synthesis of galactosylceramide (GalCer), is a significant index of tumor aggressiveness and a potential marker for the prognostic evaluation of lung metastases in breast cancer. To further reveal the
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