推荐产品
化驗
≥95%
形狀
powder
mp
153-155 °C (lit.)
SMILES 字串
[O-][N+](=O)c1ccc2ccc3cccc4ccc1c2c34
InChI
1S/C16H9NO2/c18-17(19)14-9-7-12-5-4-10-2-1-3-11-6-8-13(14)16(12)15(10)11/h1-9H
InChI 密鑰
ALRLPDGCPYIVHP-UHFFFAOYSA-N
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生化／生理作用
强效诱变剂、致癌物、环境污染物。
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Eun-Jung Park et al.
Toxicology letters, 184(2), 126-133 (2008-12-02)
Nitropyrene (1-NP) is classified as Group 2B carcinogen and is one of the main components of diesel exhaust particles (DEP), which are generated from incomplete combustion of automobile engines to cause human cancer or inflammatory diseases. Although many reports on
Mechanisms involved in lipid accumulation and apoptosis induced by 1-nitropyrene in Hepa1c1c7 cells.
N Podechard et al.
Toxicology letters, 206(3), 289-299 (2011-08-30)
1-Nitropyrene (1-NP) is a nitro-polycyclic aromatic hydrocarbon (nitro-PAH) present in diesel exhaust and bound to particular matter in urban air. We show that 1-NP and the referent PAH benzo(a)pyrene (BP) induce apoptosis and a lipid accumulation dependent on cytochrome P450
Matthew A Ratcliff et al.
Environmental science & technology, 44(21), 8343-8349 (2010-10-05)
The impacts of biodiesel and a continuously regenerated (catalyzed) diesel particle filter (DPF) on the emissions of volatile unburned hydrocarbons, carbonyls, and particle associated polycyclic aromatic hydrocarbons (PAH) and nitro-PAH, were investigated. Experiments were conducted on a 5.9 L Cummins
Lalla Rajaa Rhenimi et al.
Journal of radiation research, 49(6), 615-622 (2008-09-09)
Nitropyrene, a mutagenic and carcinogenic component of diesel exhaust, has been shown to be a potent bacterial and mammalian mutagen. There is, however, some controversy regarding the genotoxic effects of 1-nitropyrene towards yeast. To obtain insights into the mechanisms of
Carlos E Crespo-Hernández et al.
The journal of physical chemistry. A, 112(28), 6313-6319 (2008-06-25)
Femtosecond broadband transient absorption experiments of 1-nitropyrene, a nitro-polycyclic aromatic hydrocarbon of environmental concern are presented in cyclohexane and hexane solutions. The transient absorption spectra show the presence of three species that are assigned to the Franck-Condon excited lowest singlet
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