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Merck

MAK482

Sigma-Aldrich

Lipase Assay Kit

sufficient for 100 colorimetric tests

别名:

Lipase Activity Assay Kit

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About This Item

分類程式碼代碼:
12352204
NACRES:
NA.84

品質等級

檢測方法

colorimetric

相關疾病

genitourinary disorders; gastrointestinal diseases; cancer

運輸包裝

ambient

儲存溫度

2-8°C

一般說明

Lipase catalyzes the hydrolysis of ester bonds on the glycerol backbone of a lipid substrate. In humans, pancreatic lipase is the key enzyme responsible for breaking down fats in the digestive system by converting triglycerides to monoglycerides and free fatty acids. Human pancreatic lipase and its related protein 2 are the main lipases secreted by the pancreas. In acute pancreatitis, lipase levels can rise 5 to 10-fold within 24 to 48 hours. Increased activities have also been associated with pancreatic duct obstruction, pancreatic cancer, kidney disease, salivary gland inflammation, bowel obstruction, and other pancreatic diseases. Decreased levels may indicate permanent damage to lipase-producing cells in the pancreas.

特點和優勢

  • The linear detection range of the kit is 40 to 1600 U/L lipase

適合性

The kit is suitable for detecting lipase activity in serum, plasma, saliva, urine and other biological samples.

原則

The Lipase Assay Kit is based on an improved Dimercaptopropanol tributyrate (BALB) method, in which SH groups formed from lipase cleavage of BALB react with 5,5′-dithiobis (2-nitrobenzoic acid) (DTNB) to form a yellow-colored product. The color intensity, measured at 412 nm, is proportionate to the enzyme activity in the sample.

訊號詞

Danger

危險分類

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 3


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