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Merck
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MAK071

Sigma-Aldrich

丙酮酸检测试剂盒

sufficient for 100 colorimetric or fluorometric tests

别名:

Assay Kit for Pyruvate Detection

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About This Item

分類程式碼代碼:
12161503
NACRES:
NA.84

用途

sufficient for 100 colorimetric or fluorometric tests

檢測方法

colorimetric
fluorometric

相關疾病

gastrointestinal diseases; cancer

儲存溫度

−20°C

基因資訊

human ... PKLR(5313) , PKM2(5315)
mouse ... PKLR(18770) , PKM2(18746)
rat ... PKLR(24651) , PKM2(25630)

一般說明

丙酮酸是代谢中的中心分子，其通过多种代谢途径进行使用和合成，其中包括糖酵解和丙氨酸的氨基转移作用。丙酮酸可在柠檬酸循环中进一步氧化，在糖异生期间转化为碳水化合物，或还原为乳酸。高水平的丙酮酸与肝脏疾病和遗传性疾病有关。丙酮酸也被用于刺激代谢，从而导致体重减轻。

適合性

适于测定血液、组织、培养细胞等多种生物样品中的丙酮酸浓度。

原則

由偶联酶测定法测定丙酮酸浓度，得到的比色（570nm）/荧光（λex = 535/λem =587 nm）产物与存在丙酮酸成比例。

取代透過

产品编号
说明
价格

象形圖

Health hazard
GHS08

訊號詞

Danger

危險聲明

H317,H334,H412

危險分類

Aquatic Chronic 3 - Resp. Sens. 1 - Skin Sens. 1

儲存類別代碼

10 - Combustible liquids

分析证书(COA)

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Abstracts of the XVIth International Conference on Biological Inorganic Chemistry, July 22-26, 2013, Grenoble, France.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 19 Suppl 1, 1-696 (2014-03-13)
Lauren K Wareham et al.
Antioxidants & redox signaling, 24(17), 1013-1028 (2016-02-26)
Carbon monoxide is a respiratory poison and gaseous signaling molecule. Although CO-releasing molecules (CORMs) deliver CO with temporal and spatial specificity in mammals, and are proven antimicrobial agents, we do not understand the modes of CO toxicity. Our aim was
Changes in muscle cell metabolism and mechanotransduction are associated with myopathic phenotype in a mouse model of collagen VI deficiency.
De Palma S, et al.
PLoS ONE, 8(2), e56716-e56716 (2013)
Sara De Palma et al.
PloS one, 8(2), e56716-e56716 (2013-02-26)
This study identifies metabolic and protein phenotypic alterations in gastrocnemius, tibialis anterior and diaphragm muscles of Col6a1(-/-) mice, a model of human collagen VI myopathies. All three muscles of Col6a1(-/-) mice show some common changes in proteins involved in metabolism
Xiaolong Zhang et al.
Biotechnology and bioengineering, 115(9), 2217-2231 (2018-06-14)
N-acetylneuraminic acid (NeuAc) is widely used as a nutraceutical for facilitating infant brain development, maintaining brain health, and enhancing immunity. Currently, NeuAc is mainly produced by extraction from egg yolk and milk, or via chemical synthesis. However, its low concentration
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