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Merck
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主要文件

L7770

Sigma-Aldrich

脂多糖 来源于肠沙门氏菌 肠炎血清型

γ-irradiated, BioXtra, suitable for cell culture

别名:

LPS

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About This Item

MDL编号:
MFCD00131520
UNSPSC代码:
12352201
NACRES:
NA.75

生物来源

Salmonella enterica (Serotype enteritidis)

质量水平

200

无菌性

γ-irradiated

产品线

BioXtra

表单

lyophilized powder

纯化方式

gel-filtration chromatography

技术

cell culture | mammalian: suitable

杂质

<1% Protein (Lowry)

颜色

white to yellow cast

溶解性

water: 4.90-5.10 mg/mL, faintly hazy to hazy, colorless

储存温度

2-8°C

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相关类别

应用

来自血清型肠炎沙门氏菌的脂多糖可用于细胞培养和细胞结合应用。它被用于研究炎症在神经病理性疼痛和动脉瘤进展中的作用。
脂多糖 (LPS) 是革兰氏阴性菌细胞壁的特征性成分。LPS 及其脂质 A 部分通过 Toll 样受体 4 (TLR4) 刺激天然免疫系统的细胞。

生化/生理作用

脂多糖（LPS）是革兰氏阴性细菌细胞壁的特征组分。LPS及其脂质A部分可通过Toll样受体4（TLR4）刺激细胞的先天免疫系统，Toll样受体4是Toll样受体蛋白家族的成员，其可识别常见的病原体相关分子模式（PAMP）。

其他说明

为了全面了解我们针对客户研究提供的各种脂多糖产品，建议您访问我们的碳水化合物分类页面。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000403178
0000349958
0000301667
0000310456
0000403178

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Anita Mikołajczyk et al.
Gut pathogens, 9, 73-73 (2017-12-20)
The present research was conducted to investigate the influence of a low, single dose of LPS, which does not result in any clinical symptoms of intoxication on the expression of selected neuropeptides within the intestines of the domestic pig. This
Christopher J Neufeldt et al.
PLoS pathogens, 9(10), e1003744-e1003744 (2013-11-10)
Hepatitis C virus (HCV) infection induces formation of a membranous web structure in the host cell cytoplasm where the viral genome replicates and virions assemble. The membranous web is thought to concentrate viral components and hide viral RNA from pattern
Ryan Gene Soderquist et al.
Pharmaceutical research, 27(5), 841-854 (2010-03-13)
Interleukin-10 (IL-10) is an anti-inflammatory molecule that has achieved interest as a therapeutic for neuropathic pain. In this work, the potential of plasmid DNA-encoding IL-10 (pDNA-IL-10) slowly released from biodegradable microparticles to provide long-term pain relief in an animal model
Elisabetta Liverani et al.
Journal of leukocyte biology, 95(2), 313-323 (2013-10-22)
Thienopyridines are a class of antiplatelet drugs that are metabolized in the liver to several metabolites, of which only one active metabolite can irreversibly antagonize the platelet P2Y12 receptor. Possible effects of these drugs and the role of activated platelets
Rosemary Fernandez et al.
Bio-protocol, 5(11) (2016-05-03)
The ability to assess the function of a range of cytokine, antigen receptor, and Toll-like receptor (TLR) signaling pathways in a range of immune cells could provide a kind of fingerprint of the state of the human immune system. The
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