K0265

Anti-Potassium Channel K_2P4.1 (TRAAK) 兔抗

affinity isolated antibody, lyophilized powder

• 别名: Anti-KCNK4, Anti-TWIK-related arachidonic acid-stimulated K⁺ channel
• MDL號碼: MFCD09753858
• 分類程式碼代碼: 12352203
• NACRES: NA.41

属性

• 生物源: rabbit
• 品質等級: 200
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: lyophilized powder
• 物種活性: human, rat
• 技術: immunohistochemistry: suitable; western blot: 1:200 using HEK-K_2P4.1 transfected cells or rat cerebellum lysate
• UniProt登錄號: Q9NYG8
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... KCNK4(50801) ; rat ... Kcnk4(116489)

说明

一般說明

The gene K2P4.1, also referred to as KCNK4 (potassium two pore domain channel subfamily K member 4), encodes a protein belonging to the subfamily of K2P (two pore domain K⁺ channel) channels called TRAAK (TWIK-related arachidonic acid-stimulated K⁺ channel). The TRAAK channels are expressed selectively in the nervous system. TRAAK channel contains two protomers, each with two distinct pore domains forming a two-fold symmetric potassium channel.

特異性

The K_2P4.1 antibody is directed against a highly conserved epitope in the intraracellular C-terminal region of the human K_2P4.1 channel.

免疫原

peptide NLAFIDESSDTQSERGC, corresponding to amino acid residues 343-359 of human K_2P4.1.

生化／生理作用

The gene KCNK4 (potassium two pore domain channel subfamily K member 4) encodes a potassium channel that is mechanosensitive and is regulated by polyunsaturated fatty acids and temperature. The structure and chemical composition of the lipid bilayer has a profound effect on the functioning of this K⁺ channel. It is found to regulate the noxious input threshold in dorsal root ganglia neurons.

外觀

Lyophilized powder from phosphate buffered saline, pH 7.4, containing 1% BSA and 0.025% sodium azide.

重構

Reconstitute the lyophilized vial with 50 μL or 200 μL deionized water, depending on package size. Further dilutions should be made using a carrier protein, such as BSA (1-3%).

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: nwg
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable