跳转至内容
Merck

I4777

Sigma-Aldrich

干扰素-γ 来源于小鼠

≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

别名:

IFN-γ

登录查看公司和协议定价


About This Item

MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.32

生物源

mouse

品質等級

重組細胞

expressed in E. coli

化驗

≥98% (SDS-PAGE)

形狀

lyophilized powder

分子量

protein 15.6 kDa

包裝

pkg of 0.1 mg

技術

cell culture | mammalian: suitable

雜質

endotoxin, tested

顏色

white

溶解度

water: soluble 1.000 mL, clear, colorless

UniProt登錄號

儲存溫度

−20°C

基因資訊

mouse ... Ifng(15978)

應用

小鼠干扰素-γ 已用于:
  • 体外 BMDC(骨髓源性树突状细胞)、BMM(骨髓源性巨噬细胞)和 CD11c + (CD11 抗原样家族成员 c)肺巨噬细胞的刺激
  • 刺激小鼠巨噬细胞,诱导产生亚硝酸盐和硝酸盐
  • 检查 CCAAT/增强子结合蛋白 β(C/EBPβ)介导的前列腺素合成酶在神经炎症中表达的变化

生化/生理作用

干扰素-γ (interferon-γ) 在天然免疫和获得性免疫应答中发挥重要作用,并有助于防御细菌感染、二型酵母和一些病毒感染。

外觀

从 0.2 μm 过滤缓冲液冻干。基于蛋白质含量的包装尺寸。

分析報告

重组小鼠 IFN-γ 的生物学活性通过其抑制鼠 WEHI-279 细胞增殖的能力进行测定。

相關產品

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Sergio Arias-Negrete et al.
Analytical biochemistry, 328(1), 14-21 (2004-04-15)
Preparation of a nitrate reductase lysate of Escherichia coli MC1061 to measure nitrate and nitrite in biologic fluids is described. To obtain the crude bacterial lysate containing nitrate reductase activity, E. coli MC1061 was subjected to 16-20 freeze-thawing cycles, from
S N Vogel et al.
Infection and immunity, 38(2), 681-685 (1982-11-01)
Silica has been used for many years as an agent which selectively alters macrophage functions and, as such, has been used to assess the role of macrophages in the immune response to a variety of microbial and chemically defined agents.
P W Gray et al.
Proceedings of the National Academy of Sciences of the United States of America, 80(19), 5842-5846 (1983-10-01)
The murine immune interferon (IFN-gamma) gene was cloned and expressed under control of the simian virus 40 early promoter in the monkey COS-1 cell line. A protein is secreted from these cells having the biological, antigenic, and biochemical characteristics of
Tatiana Cheusova et al.
Genes & development, 20(13), 1800-1816 (2006-07-05)
The release of Agrin by motoneurons activates the muscle-specific receptor tyrosine kinase (MuSK) as the main organizer of subsynaptic specializations at the neuromuscular junction. MuSK downstream signaling is largely undefined. Here we show that protein kinase CK2 interacts and colocalizes
Marta Pulido-Salgado et al.
Scientific reports, 8(1), 16096-16096 (2018-11-02)
Microglia, the main resident immune cells in the CNS, are thought to participate in the pathogenesis of various neurological disorders. LPS and LPS + IFNγ are stimuli that are widely used to activate microglia. However, the transcriptomic profiles of microglia treated with

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门