所有图片(1)
About This Item
经验公式（希尔记法）:
C20H14O2S2
CAS号:
分子量:
350.45
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77
推荐产品
品質等級
化驗
≥95% (HPLC)
形狀
powder
顏色
off-white to yellow
溶解度
DMSO: >20 mg/mL
H2O: insoluble
儲存溫度
2-8°C
SMILES 字串
Oc1ccc2ccccc2c1SSc3c(O)ccc4ccccc34
InChI
1S/C20H14O2S2/c21-17-11-9-13-5-1-3-7-15(13)19(17)23-24-20-16-8-4-2-6-14(16)10-12-18(20)22/h1-12,21-22H
InChI 密鑰
RFAXLXKIAKIUDT-UHFFFAOYSA-N
生化／生理作用
IPA-3是Pak1的变构抑制剂。它与pak1（p21激活激酶）的自身抑制结构域结合，在激酶中具有高选择性。 Pak1与肿瘤发生和转移有关。
訊號詞
Danger
危險聲明
危險分類
Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
其他客户在看
Elena G Sánchez et al.
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African swine fever (ASF) is caused by a large and highly pathogenic DNA virus, African swine fever virus (ASFV), which provokes severe economic losses and expansion threats. Presently, no specific protection or vaccine against ASF is available, despite the high
Aniruddha Das et al.
Scientific reports, 7(1), 13930-13930 (2017-10-27)
Fear conditioning, a behavioral model for studying fear-related disorders, is believed to be formed by alterations of synaptic efficacy mediated by changes in synaptic transmission and neuronal morphology in lateral amygdala (LA). Rac GTPase and its downstream effector p21-activated kinase (PAK)
Kemal Keseroglu et al.
Nature communications, 14(1), 6497-6497 (2023-10-15)
Mutations of several genes cause incomplete penetrance and variable expressivity of phenotypes, which are usually attributed to modifier genes or gene-environment interactions. Here, we show stochastic gene expression underlies the variability of somite segmentation defects in embryos mutant for segmentation
Florian Ingo Schmidt et al.
The EMBO journal, 30(17), 3647-3661 (2011-07-28)
Vaccinia virus (VACV), the model poxvirus, produces two types of infectious particles: mature virions (MVs) and extracellular virions (EVs). EV particles possess two membranes and therefore require an unusual cellular entry mechanism. By a combination of fluorescence and electron microscopy
Karla C Williams et al.
Oncogene, 38(19), 3598-3615 (2019-01-18)
Invadopodia are cell protrusions that mediate cancer cell extravasation but the microenvironmental cues and signaling factors that induce invadopodia formation during extravasation remain unclear. Using intravital imaging and loss of function experiments, we determined invadopodia contain receptors involved in chemotaxis
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