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Merck

H8759

Sigma-Aldrich

4-Hydroxy-3-methoxyphenylglycol sulfate potassium salt

≥98% (HPLC), powder

别名:

(3-Methoxy-4-sulfonyloxyphenyl)glycol potassium salt, MHPG sulfate potassium salt, MOPEG sulfate potassium salt

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About This Item

经验公式(希尔记法):
C9H11KO7S
CAS号:
分子量:
302.34
Beilstein:
4625651
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

品質等級

化驗

≥98% (HPLC)

形狀

powder

顏色

off-white

溶解度

H2O: 50 mg/mL

儲存溫度

2-8°C

SMILES 字串

[K+].COc1cc(ccc1OS([O-])(=O)=O)C(O)CO

InChI

1S/C9H12O7S.K/c1-15-9-4-6(7(11)5-10)2-3-8(9)16-17(12,13)14;/h2-4,7,10-11H,5H2,1H3,(H,12,13,14);/q;+1/p-1

InChI 密鑰

XFZJWBFZLNLKNR-UHFFFAOYSA-M

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生化/生理作用

Norepinephrine metabolite that is often used as an index of adrenergic stimulation.

特點和優勢

This compound is featured on the Dopamine and Norepinephrine Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

包裝

Bottomless glass bottle. Contents are inside inserted fused cone.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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K W Perry et al.
Journal of neural transmission (Vienna, Austria : 1996), 104(8-9), 953-966 (1997-01-01)
The selective serotonin uptake inhibitor fluoxetine (10 mg/kg i.p.) increased tissue levels of the norepinephrine metabolite 3-methoxy-4-hydroxyphenylethylene glycol sulfate (MHPG-SO4) in rat hypothalamus, indicating an increased release of norepinephrine. Microdialysis studies in conscious rats showed that fluoxetine (10 mg/kg i.p.)
E T Hellriegel et al.
Pharmacology, biochemistry, and behavior, 57(1-2), 207-214 (1997-05-01)
The objective of this investigation was to examine the immediate and long term effects of acute, chronic and chronic intermittent stress on the central noradrenergic system of rats. Male Sprague-Dawley rats were subjected to one hour of physical immobilization stress
G Eisenhofer et al.
Journal of neurochemistry, 66(4), 1565-1573 (1996-04-01)
This study used regional differences in plasma concentrations of norepinephrine and its metabolites to examine how production of the transmitter by sympathetic nerves, in particular, those innervating mesenteric organs, is integrated with metabolism by the liver and elimination by the
Phedias Diamandis et al.
Nature chemical biology, 3(5), 268-273 (2007-04-10)
The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways that governs the

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