跳转至内容
Merck
所有图片(1)

主要文件

查看所有文档

G8168

Sigma-Aldrich

G418 disulfate salt

solution, non-animal origin, suitable for cell culture, BioReagent

别名:

抗生素G418

登录查看公司和协议定价
所有图片(1)

About This Item

经验公式（希尔记法）:
C20H40N4O10 · 2H2SO4
CAS号:
108321-42-2
分子量:
692.71
MDL编号:
MFCD00058314
UNSPSC代码:
12352207
PubChem化学物质编号:
24895333
NACRES:
NA.76

产品名称

G 418 二硫酸盐 溶液, 50 mg/mL in H2O, 0.1 μm filtered, BioReagent, suitable for cell culture

生物来源

Micromonospora echinospora

质量水平

200

无菌性

0.1 μm filtered

产品线

BioReagent

表单

solution

效能

50-60 mg per mL

分子量

692.7

包装

pkg of 10 and 100 mL

浓度

50 mg/mL in H2O

技术

cell culture | mammalian: suitable

杂质

endotoxin, tested

颜色

colorless

溶解性

H2O: 50 mg/mL, clear

抗生素抗菌谱

parasites

作用机制

protein synthesis | interferes

储存温度

2-8°C

SMILES字符串

OS(O)(=O)=O.OS(O)(=O)=O.CN[C@H]1[C@H](O)[C@@H](OC[C@@]1(C)O)O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H]([C@H](C)O)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O

InChI

1S/C20H40N4O10.2H2O4S/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19;2*1-5(2,3)4/h6-19,24-30H,4-5,21-23H2,1-3H3;2*(H2,1,2,3,4)/t6?,7-,8+,9+,10+,11-,12-,13-,14+,15+,16-,17-,18+,19-,20+;;/m0../s1

InChI key

UHEPSJJJMTWUCP-NKCAIAFTSA-N

正在寻找类似产品? 访问 产品对比指南

一般描述

化学结构：氨基糖苷类

应用

G418二硫酸盐是一种氨基糖苷类抗生素，其结构与庆大霉素相似，用于选择和维持原核和真核细胞。不同细胞系具有不同的筛选和维持最佳浓度。 细菌和藻类最多需要5 μg/mL而动物细胞则可能需要300-500 μg/mL。

生化/生理作用

作用机制：G418可通过抑制70S和80S核糖体的合成来阻止多肽合成和蛋白质延伸。

抗菌谱：G418可选择经iNOS启动子构建体和新霉素抗性基因稳定转染的细胞，并显示出对原生动物和蠕虫的活性。

注意

该产品在2-8°C下可稳定储存两年。

象形图

Health hazard
GHS08

警示用语：

Danger

危险声明

H317,H334

危险分类

Resp. Sens. 1 - Skin Sens. 1

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000406785
0000406744
0000406783
0000406744
0000406785

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

其他客户在看

Slide 1 of 1

1 of 1

新霉素 三硫酸盐 水合物 powder, BioReagent, suitable for cell culture

Sigma-Aldrich

N6386

新霉素 三硫酸盐 水合物

Joan Lin-Cereghino et al.
Yeast (Chichester, England), 25(4), 293-299 (2008-03-11)
The methylotrophic yeast, Pichia pastoris, is widely used as a host organism for the expression of heterologous proteins. Currently, the Zeocin and blasticidin resistance genes are the only dominant selectable markers that can be used for primary selection of transformants.
Kelvin Kai-Wan Hui et al.
Journal of cellular and molecular medicine, 23(3), 1784-1797 (2018-12-15)
Aberrant regulation of programmed cell death (PCD) has been tied to an array of human pathologies ranging from cancers to autoimmune disorders to diverse forms of neurodegeneration. Pharmacologic modulation of PCD signalling is therefore of central interest to a number
Alaullah Sheikh et al.
Proceedings of the National Academy of Sciences of the United States of America, 117(46), 29055-29062 (2020-11-04)
The enterotoxigenic Escherichia coli (ETEC) are among the most common causes of diarrheal illness and death due to diarrhea among young children in low-/middle-income countries (LMICs). ETEC have also been associated with important sequelae including malnutrition and stunting, placing children
Denisa Jamecna et al.
Developmental cell, 49(2), 220-234 (2019-03-25)
Lipid transfer proteins (LTPs) acting at membrane contact sites (MCS) between the ER and other organelles contain domains involved in heterotypic (e.g., ER to Golgi) membrane tethering as well as domains involved in lipid transfer. Here, we show that a
Fumika Koyano et al.
EMBO reports, 20(12), e47728-e47728 (2019-10-12)
Ubiquitylation of outer mitochondrial membrane (OMM) proteins is closely related to the onset of familial Parkinson's disease. Typically, a reduction in the mitochondrial membrane potential results in Parkin-mediated ubiquitylation of OMM proteins, which are then targeted for proteasomal and mitophagic
查看所有相关文献

商品

Safe Lentivirus Handling

Lentiviral vector systems prioritize safety features, with design precautions preventing replication. Good handling practices are essential for use.

Safe Lentivirus Handling

Lentiviral vector systems prioritize safety features, with design precautions preventing replication. Good handling practices are essential for use.

Safe Lentivirus Handling

Lentiviral vector systems prioritize safety features, with design precautions preventing replication. Good handling practices are essential for use.

Safe Lentivirus Handling

Lentiviral vector systems prioritize safety features, with design precautions preventing replication. Good handling practices are essential for use.

查看所有结果

实验方案

CRISPR Lentiviral Screening: Antibiotic Selection

Lentivirus versions of genome modification technologies support successful CRISPR, RNAi, and ORF experiments.

CRISPR Lentiviral Screening: Antibiotic Selection

Lentivirus versions of genome modification technologies support successful CRISPR, RNAi, and ORF experiments.

CRISPR Lentiviral Screening: Antibiotic Selection

Lentivirus versions of genome modification technologies support successful CRISPR, RNAi, and ORF experiments.

CRISPR Lentiviral Screening: Antibiotic Selection

Lentivirus versions of genome modification technologies support successful CRISPR, RNAi, and ORF experiments.

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门