E4375

(-)-肾上腺素 (+)-酒石酸氢盐

solid, adrenergic receptor agonist

• 别名: 酒石酸肾上腺素, 副肾素 (+)-酒石酸氢盐, L-3,4-Dihydroxy-α-(methylaminomethyl)benzyl alcohol D-hydrogen 酒石酸氢盐, L-Adrenaline D-hydrogentartrate
• 经验公式（希尔记法）: C₉H₁₃NO₃ · C₄H₆O₆
• CAS号: 51-42-3
• 分子量: 333.29
• EC號碼: 200-097-1
• MDL號碼: MFCD00035077
• 分類程式碼代碼: 12352200
• PubChem物質ID: 24277774
• NACRES: NA.77

属性

• 产品名称: (-)-肾上腺素 (+)-酒石酸氢盐, solid
• 形狀: solid
• 品質等級: 200
• 顏色: white
• 溶解度: H₂O: soluble; alcohol: soluble
• 儲存溫度: 2-8°C
• SMILES 字串: O[C@H]([C@@H](O)C(O)=O)C(O)=O.CNC[C@H](O)c1ccc(O)c(O)c1
• InChI: 1S/C9H13NO3.C4H6O6/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;5-1(3(7)8)2(6)4(9)10/h2-4,9-13H,5H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t9-;1-,2-/m01/s1
• InChI 密鑰: YLXIPWWIOISBDD-NDAAPVSOSA-N
• 基因資訊: human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152) , ADRB1(153) , ADRB2(154) , ADRB3(155)

说明

一般說明

Epinephrine is a hormone, which is also termed as adrenaline. It is a monoamine and catecholamine.[1]

應用

(-)Epinephrine (+)-bitartrate salt has been used:

• to test the possible existence of β-adrenergic vasodilation[2]
• to infuse into the adipose region to minimize blood loss and tissue contamination[3]
• as a platelet agonist in the preparation of optimal platelet aggregometry 96-well plates[4]
• in the measurement of total superoxide dismutase (tSOD) enzymatic activity[5]

生化／生理作用

肾上腺素能受体激动剂。

Epinephrine is mainly liberated from adrenal medulla in response to stress, that is facilitated through sympathetic fibers.[6]

特點和優勢

This compound is featured on the α1-Adrenoceptors, α2-Adrenoceptors, β-Adrenoceptors and Dopamine, Norepinephrine and Epinephrine Synthesis pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

注意

Light sensitive

安全信息

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H300
• 防範說明: P264 - P270 - P301 + P310 - P405 - P501
• 危險分類: Acute Tox. 1 Oral
• 儲存類別代碼: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges