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Key Documents

D9565

Sigma-Aldrich

β-Defensin 1 human

≥98% (HPLC and SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder (from 10 mM acetic acid)

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About This Item

MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.32

重組細胞

expressed in E. coli

化驗

≥98% (HPLC and SDS-PAGE)

形狀

lyophilized powder (from 10 mM acetic acid)

分子量

estimated mol wt 3.9 kDa

UniProt登錄號

抗生素活性譜

Gram-negative bacteria
Gram-positive bacteria
fungi
viruses

作用方式

cell wall synthesis | interferes

儲存溫度

−20°C

基因資訊

human ... DEFB1(1672)

Amino Acid Sequence

Asp-His-Tyr-Asn-Cys-Val-Ser-Ser-Gly-Gly-Gln-Cys-Leu-Tyr-Ser-Ala-Cys-Pro-Ile-Phe-Thr-Lys-Ile-Gln-Gly-Thr-Cys-Tyr-Arg-Gly-Lys-Ala-Lys-Cys-Cys-Lys [Disulfide bridges 5-34, 12-27, and 17-35]

一般說明

Chemical structure: peptide

生化/生理作用

A small cationic peptide which demonstrates anti-microbial activity. Originally isolated from human plasma, this substance is constitutively expressed in mucosal membrane epithelium.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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由于细菌耐药性和新出现的传染病成为人类的潜在威胁,核糖体合成的抗菌肽已成为抗生素研究的一个有前途的重点领域。

Ribosomally synthesized antimicrobial peptides are a promising focus in antibiotic research amidst bacterial resistance and emerging infectious diseases.

Ribosomally synthesized antimicrobial peptides are a promising focus in antibiotic research amidst bacterial resistance and emerging infectious diseases.

Ribosomally synthesized antimicrobial peptides are a promising focus in antibiotic research amidst bacterial resistance and emerging infectious diseases.

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