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Merck

D7137

Sigma-Aldrich

二羟丙酮磷酸盐 二锂盐

≥93% dry basis (enzymatic)

别名:

1,3-二羟基-2-丙酮1-磷酸酯 二锂盐, 1-羟基-3-(膦酰氧基)-2-丙酮 二锂盐, DHAP

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About This Item

经验公式(希尔记法):
C3H5Li2O6P
分子量:
181.92
Beilstein:
1708891
MDL號碼:
分類程式碼代碼:
12352201
PubChem物質ID:
NACRES:
NA.25

生物源

bovine (casein)

品質等級

化驗

≥93% dry basis (enzymatic)

形狀

powder

雜質

~0.2 mol % D-glyceraldehyde 3-phosphate

顏色

white

溶解度

soluble 50mg plus 1ml of H2O, clear, colorless to faintly yellow

負離子痕跡

phosphate (PO43-): ~5 mol %

正離子痕跡

Li: 5.5-8.0% (dry basis)

儲存溫度

−20°C

SMILES 字串

[Li+].[Li+].OCC(=O)COP([O-])([O-])=O

InChI

1S/C3H7O6P.2Li/c4-1-3(5)2-9-10(6,7)8;;/h4H,1-2H2,(H2,6,7,8);;/q;2*+1/p-2

InChI 密鑰

QWIKESRFRWLYIA-UHFFFAOYSA-L

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應用

磷酸二羟丙酮(DHAP)被用于果糖代谢、丙糖和糖化研究中。它被用于涉及三碳糖池代谢及其在生理和物理过程中作用的研究中。DHAP可用作底物以帮助鉴定、区分和表征果糖-二磷酸醛缩酶(ALDOA)和磷酸丙糖异构酶。DHAP可被用于研究细胞糖化应激。

生化/生理作用

磷酸二羟丙酮(DHAP)是一种参与到多种通路中的代谢中间体,包括糖酵解、糖异生、甘油代谢、磷脂酸合成、脂肪代谢和卡尔文循环。

注意

与二甲基缩酮不同,在用作底物前不需要水解。

準備報告

酶制剂。

其他說明

为了全面了解我们针对客户研究提供的各种单糖产品,建议您访问我们的碳水化合物分类页面。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Non-enzymatic glycation is the addition of free carbonyl group of reducing sugar to the free amino groups of proteins, resulting in the formation of a Schiff base and an Amadori product. Dihydroxyacetone (DHA) is one of the carbonyl species which
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Scientific reports, 7(1), 15170-15170 (2017-11-11)
Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry has been widely used for biomolecular analysis. However, with conventional MALDI, it is difficult to analyse low-molecular-weight compounds because of the interference of matrix ion signals. Here, we report a matrix-free on-chip pulse-heating desorption/ionization
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Sugar-derived reactive carbonyls (RCs), including methylglyoxal (MG), are aggressive by-products of oxidative stress known to impair the functions of multiple proteins. These advanced glycation end-products accumulate in patients with diabetes mellitus and cause major complications, including arteriosclerosis and cardiac insufficiency.
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