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Merck

D3072

Sigma-Aldrich

盐酸多西环素,现成溶液

别名:

α-6-脱氧-5-羟基四环素盐酸盐, 2-并四苯甲酰胺, 4-(二甲氨基)- 1,4,4a,5,5a,6,11,12a-八氢-3,5,10,12,12a-五羟基-6-甲基-1,11-二氧-,盐酸盐(1:1),(4S,4aR,5S,5aR,6R,12aS)-, Doxylin, Idocyklin, 盐酸多西环素, 盐酸强力霉素

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About This Item

经验公式(希尔记法):
C22H24N2O8 · HCl
CAS号:
分子量:
480.90
MDL號碼:
分類程式碼代碼:
51284028
NACRES:
NA.85

生物源

synthetic

品質等級

無菌

0.22 μm filtered

形狀

liquid

濃度

100 mg/mL in DMSO

溶解度

DMSO: 100 mg/mL

抗生素活性譜

Gram-negative bacteria
Gram-positive bacteria
mycoplasma
parasites

作用方式

protein synthesis | interferes

儲存溫度

−20°C

InChI

1S/C22H24N2O8.ClH/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;/h4-7,10,14-15,17,25-27,31-32H,23H2,1-3H3;1H/b21-13-;/t7-,10+,14+,15-,17-,22-;/m0./s1

InChI 密鑰

VLUQVUWDECWBTL-UQVCFKGQSA-N

一般說明

强力霉素是一种四环素类抗生素,通常用于治疗各种感染。它是一种广谱抗生素和抑菌剂。强力霉素具有抗原生动物特性,是体内MMPs(基质金属蛋白酶)的有效抑制剂。

應用

<ul>
<li><strong>AAPS PharmSciTech: </strong>Creation of a PVA/PCL/CS-based nanofibrous membrane incorporating doxycycline hydrochloride for guided tissue regeneration and controlled delivery in the management of periodontitis, evaluated in vivo in rats (Mirzaeei et al., 2024).</li>
<li><strong>European Journal of Pharmacology: </strong>Doxycycline hydrochloride′s role in inhibiting the progression of malignant rhabdoid tumor of the kidney by targeting MMP17 and MMP1 through the PI3K-Akt signaling pathway (Mi et al., 2024).</li>
</ul>

其他說明

保持容器密闭,并置于干燥通风处。打开后的容器必须小心重新密封并保持直立以防止泄漏。

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

188.6 °F - closed cup

閃點(°C)

87 °C - closed cup


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