CN406-05

Canine Osteoblasts: CnOb (Cryovial)

• UNSPSC代码: 41106514
• NACRES: NA.81

属性

• 生物来源: canine bone (normal)
• 包装: pkg of 500,000 cells
• 制造商/商品名称: Cell Applications, Inc
• 生长模式: Adherent
• 核型: 2n = 78
• 形态学: osteoblast
• 技术: cell culture | mammalian: suitable
• 相关疾病: arthritis; osteoporosis
• 运输: dry ice
• 储存温度: −196°C

说明

一般描述

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Canine osteoblasts provide an excellent model system for studies relevant to the skeletal system, including mechanisms of cancerogenesis.

Canine osteoblasts have been used to define a biomarker profile of canine osteosarcoma (Milovancev, 2013), elucidate the roles of oncogenic STAT3 (Fossey, 2009, 2011) and canonical Wnt signaling (Piskun, 2013) pathways, and to develop personalized osteosarcoma treatments by testing Src inhibitor dasatinib (Davis, 2013), procaspase-3 activating compound PAC-1 (Book, 2012), HSP90 inhibitor STA-1474 (McCleese, 2009) and STAT3 inhibitor LLL12 (Couto, 2012, 2013).

Characterization: Positive for bone mineralization.

细胞系来源

Bone

应用

model for skeletal system research, signaling pathways, bone morphogenesis, gene expression, cell activation and proliferation, wound healing, bone formation and regeneration, treatment strategies, tissue engineering, in vitro bone models, mineralization, hormone treatments

组分

Canine Osteoblast Basal Medium containing 10% FBS & 10% DMSO

制备说明

• 1st passage, >500,000 cells in Canine Osteoblast Basal Medium containing 10% FBS & 10% DMSO
• Can be cultured at least 10 doublings

传代培养常规

Please refer to the CnOb Culture Protocol.

安全信息

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable