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應用
消胆胺树脂可用于:
- 作为膳食补充剂,研究小鼠胆汁酸池大小和粪便胆汁酸排出量
- 改变胆汁酸(BA)水平,研究其对野生型(WT)、成纤维生长因子15(Fgf15)−/−和Fgf15转基因(TG)小鼠肝纤维化发展的影响
- 参与体外消化过程,研究其结合胆汁酸(BA)的能力
消胆胺树脂用于蛋白质层析、离子交换层析和阴离子交换介质。考来烯胺已被用于研究缓解胆囊切除术后腹泻、管理顽固性胆汁淤积性瘙痒和肥胖。
生化/生理作用
消胆胺是一种阳离子交换树脂。这种树脂可作为胆汁酸螯合剂,所含氯离子与小肠腔胆汁酸交换后,螯合的胆汁酸从粪便排出,使血清胆汁酸水平下降。消胆胺也用于治疗原发性高胆固醇血症。这种树脂可使低密度脂(LDL)胆固醇剂量依赖性减少。降低冠心病风险。
其他說明
交联聚苯乙烯上的季铵盐官能团
法律資訊
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 2
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
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