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Merck
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主要文件

C1613

Sigma-Aldrich

羧苄西林

Ready Made Solution, 100 mg/mL in ethanol/water, 0.2 μm filtered

别名:

α-羧苄青霉素 溶液

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About This Item

经验公式（希尔记法）:
C17H18N2O6S
分子量:
378.40
MDL编号:
MFCD00242604
UNSPSC代码:
51282404
PubChem化学物质编号:
24892425
NACRES:
NA.85
价格与库存信息目前不能提供

质量水平

200

无菌性

0.2 μm filtered

表单

liquid

浓度

100 mg/mL in ethanol/water

溶解性

H2O: 100 mg/mL
ethanol: 100 mg/mL

适用性

suitable for testing specifications (Bacteriostatic (cell type) E. Coli DH5a, result: pass)

抗生素抗菌谱

Gram-negative bacteria
Gram-positive bacteria

作用机制

cell wall synthesis | interferes

运输

wet ice

储存温度

−20°C

SMILES字符串

CC1(C)S[C@@H]2[C@H](NC(=O)C(C(O)=O)c3ccccc3)C(=O)N2[C@H]1C(O)=O

InChI

1S/C17H18N2O6S/c1-17(2)11(16(24)25)19-13(21)10(14(19)26-17)18-12(20)9(15(22)23)8-6-4-3-5-7-8/h3-7,9-11,14H,1-2H3,(H,18,20)(H,22,23)(H,24,25)/t9?,10-,11+,14-/m1/s1

InChI key

FPPNZSSZRUTDAP-UWFZAAFLSA-N

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相关类别

一般描述

化学结构:β-内酰胺

应用

羧苄青霉素(Carbenicillin)可用于筛选氨苄青霉素抗性转化细胞。还可用于研究青霉素敏感的转肽酶在细胞壁生物合成中的作用。

生化/生理作用

羧苄西林(Carbenicillin)是一种氨苄西林类似物，具有苄基青霉素结构。羧苄西林可有效抑制革兰氏阴性菌，对革兰氏阳性菌也有一定的抑制作用。羧苄西林结合并抑制参与细菌细胞壁合成的酶。由于羧苄西林对β-内酰胺酶的敏感性弱于氨苄西林，它可有效抑制氨苄西林抗性细菌。在低pH条件下具有优越的稳定性，可发挥筛选功能。 羧苄西林的有效浓度：50-100 μg/ml。

其他说明

保持容器密闭，并置于干燥通风处。打开后的容器必须小心重新密封并保持直立以防止泄漏。

象形图

FlameHealth hazard
GHS02,GHS08

警示用语：

Danger

危险声明

H226,H317,H334

危险分类

Flam. Liq. 3 - Resp. Sens. 1 - Skin Sens. 1

储存分类代码

3 - Flammable liquids

WGK

WGK 2

闪点(°F)

104.0 °F - closed cup

闪点(°C)

40 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000366369
0000209011
0000366369
0000209011
0000161550

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A J Wright
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The penicillin family of antibiotics remains an important part of our antimicrobial armamentarium. In general, these agents have bactericidal activity, excellent distribution throughout the body, low toxicity, and efficacy against infections caused by susceptible bacteria. The initial introduction of aqueous
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