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Merck

B9156

Sigma-Aldrich

Butorphanol (+)-tartrate salt

≥99%

别名:

L-N-Cyclobutylmethyl-3,14-dihydroxymorphinan (+)-tartrate salt

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About This Item

经验公式(希尔记法):
C21H29NO2 · C4H6O6
CAS号:
分子量:
477.55
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

品質等級

化驗

≥99%

形狀

powder

藥物控制

USDEA Schedule IV; psychotrope (France); regulated under CDSA - not available from Sigma-Aldrich Canada

起源

Bristol-Myers Squibb

儲存溫度

2-8°C

SMILES 字串

O[C@H]([C@@H](O)C(O)=O)C(O)=O.Oc1ccc2C[C@H]3N(CC[C@@]4(CCCC[C@@]34O)c2c1)CC5CCC5

InChI

1S/C21H29NO2.C4H6O6/c23-17-7-6-16-12-19-21(24)9-2-1-8-20(21,18(16)13-17)10-11-22(19)14-15-4-3-5-15;5-1(3(7)8)2(6)4(9)10/h6-7,13,15,19,23-24H,1-5,8-12,14H2;1-2,5-6H,(H,7,8)(H,9,10)/t19-,20+,21-;1-,2-/m11/s1

InChI 密鑰

GMTYREVWZXJPLF-BTVKVFNOSA-N

基因資訊

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生化/生理作用

κ/μ opioid receptor agonist.

特點和優勢

This compound was developed by Bristol-Myers Squibb. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

象形圖

Health hazardExclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral - Repr. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


分析证书(COA)

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J A Vivian et al.
The Journal of pharmacology and experimental therapeutics, 290(1), 259-265 (1999-06-25)
Butorphanol and nalbuphine have substantial affinity for mu and kappa-opioid receptor sites, yet their behavioral effects in monkeys are largely consistent with a mu receptor mechanism of action. Using ethylketocyclazocine (EKC) discrimination and diuresis assays in rhesus monkeys (Macaca mulatta)
J C Chen et al.
Life sciences, 52(4), 389-396 (1993-01-01)
The ability of morphine, fentanyl, butorphanol, nalbuphine, and dezocine to compete with radiolabeled ligands for binding at the mu1, mu2, kappa1, and delta opioid receptors and the sigma receptor was characterized. In the absence of sodium, the potency of opioid

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