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Merck

AV01005

Sigma-Aldrich

Anti-BCL2 antibody produced in rabbit

affinity isolated antibody

别名:

Anti-B-cell CLL/lymphoma 2

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

26 kDa

物種活性

human

濃度

0.5 mg - 1 mg/mL

技術

immunohistochemistry: suitable
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... BCL2(596)

一般說明

BCL2 is an apoptotic inhibitor that suppresses lipid peroxidation. Rabbit Anti-BCL2 antibody binds to human BCL2.

免疫原

Synthetic peptide directed towards the N terminal region of human BCL2

應用

Rabbit Anti-BCL2 antibody can be used for immunohistochemistry (4-8μg/ml, using paraffin embedded tissues) and western blot (1.0μg/ml) assays.
Western blot analysis was performed on NK-cell lymphoma and Leukemia cell lysates using rabbit anti-BCL2 antibody.

序列

Synthetic peptide located within the following region: GHTPHPAASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDD

外觀

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Slide 1 of 1

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D M Hockenbery et al.
Cell, 75(2), 241-251 (1993-10-22)
Bcl-2 inhibits most types of apoptotic cell death, implying a common mechanism of lethality. Bcl-2 is localized to intracellular sites of oxygen free radical generation including mitochondria, endoplasmic reticula, and nuclear membranes. Antioxidants that scavenge peroxides, N-acetylcysteine and glutathione peroxidase

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