跳转至内容
Merck

A5486

Sigma-Aldrich

偶氮甲烷

13.4 M, ≥98%

别名:

AOM

登录查看公司和协议定价


About This Item

线性分子式:
CH3N=N(→O)CH3
CAS号:
分子量:
74.08
MDL號碼:
分類程式碼代碼:
12352124
PubChem物質ID:
NACRES:
NA.25

化驗

≥98%

形狀

liquid

成份

methylene chloride, ≤1% (solvent)

儲存條件

(Keep container tightly closed in a dry and well-ventilated place.)

濃度

13.4 M

顏色

colorless

bp

97-99 °C (lit.)

密度

0.991 g/mL at 25 °C (lit.)

應用

genomic analysis

儲存溫度

−20°C

SMILES 字串

C\N=[N+](/C)[O-]

InChI

1S/C2H6N2O/c1-3-4(2)5/h1-2H3/b4-3+

InChI 密鑰

DGAKHGXRMXWHBX-ONEGZZNKSA-N

正在寻找类似产品? 访问 产品对比指南

一般說明

偶氮甲烷(AOM)是一种功能强大的实验室化学品,用于研究癌症,特别是结肠癌的发生、进展和预防。它可用作引发肿瘤形成的致癌物和导致DNA特异性改变的基因突变剂。

應用

氧化偶氮甲烷(AOM),一种基因突变剂,可与硫酸葡聚糖钠(DSS)一起用于在实验室动物中创建癌症模型,从而用于研究癌症进展和化学预防的机制。

生化/生理作用

诱导DNA中O6-甲基鸟嘌呤加合物的致癌物导致G→A转变。 在实验动物的结肠中诱导肿瘤生成,并用于研究癌症进展和化学预防的机制。

特點和優勢

用途广泛,适用于各种实验室和研究应用。

其他說明

为避免实验动物过早死亡,在实验设计中确定合适的氧化偶氮甲烷剂量至关重要。
如需了解生化试剂系列的更多信息,请填写此表

相關產品

产品编号
说明
价格

訊號詞

Danger

危險分類

Acute Tox. 2 Oral - Carc. 1B - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

75.2 °F

閃點(°C)

24 °C


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Eva Pastille et al.
PLoS pathogens, 13(9), e1006649-e1006649 (2017-09-25)
Inflammatory bowel diseases (IBD) are chronic inflammatory disorders of the gastrointestinal tract, strongly associated with an increased risk of colorectal cancer development. Parasitic infections caused by helminths have been shown to modulate the host's immune response by releasing immunomodulatory molecules
Sonia Leon-Cabrera et al.
Cancers, 10(9) (2018-09-22)
Signal transducer and activator of transcription 1 (STAT1) is part of the Janus kinase (JAK/STAT) signaling pathway that controls critical events in intestinal immune function related to innate and adaptive immunity. Recent studies have implicated STAT1 in tumor⁻stroma interactions, and
Carlotta Tacconi et al.
Cancer research, 79(16), 4196-4210 (2019-06-27)
Colorectal cancer is a major cause of cancer-related death in Western countries and is associated with increased numbers of lymphatic vessels (LV) and tumor-associated macrophages (TAM). The VEGFC/VEGFR3 pathway is regarded as the principal inducer of lymphangiogenesis and it contributes
Shiyan Wang et al.
Cancer research, 79(16), 4086-4098 (2019-06-27)
Tripartite motif (TRIM) family proteins participate in a variety of important cellular processes, including apoptosis, cell-cycle arrest, DNA repair, and senescence. In this study, we demonstrated that a novel TRIM family member, TRIM67, was commonly silenced in colorectal cancer and
Anne Chastre et al.
PloS one, 7(11), e49670-e49670 (2012-11-21)
Acute liver failure (ALF) due to ischemic or toxic liver injury is a clinical condition that results from massive loss of hepatocytes and may lead to hepatic encephalopathy (HE), a serious neuropsychiatric complication. Although increased expression of tumor necrosis factor-alpha

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门