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About This Item
经验公式（希尔记法）:
C4H12NaNO7P2 · 3 H2O
CAS号:
分子量:
325.12
MDL编号:
UNSPSC代码:
41106300
PubChem化学物质编号:
NACRES:
NA.77
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方案
≥97% (NMR)
表单
powder
颜色
white
溶解性
water, double-distilled: 10 mg/mL
储存温度
−20°C
SMILES字符串
[Na+].[H]O[H].[H]O[H].[H]O[H].NCCCC(O)(P(O)(O)=O)P(O)([O-])=O
InChI
1S/C4H13NO7P2.Na.3H2O/c5-3-1-2-4(6,13(7,8)9)14(10,11)12;;;;/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12);;3*1H2/q;+1;;;/p-1
InChI key
DCSBSVSZJRSITC-UHFFFAOYSA-M
基因信息
human ... FDPS(2224)
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应用
阿仑膦酸钠三水合物已被用于：钛植入物的磷酸钙纳米颗粒（nCaP）二膦酸盐（BP）涂层并用于分析其成骨能力 从老年骨质疏松症患者和健康人群中分离的人骨髓基质细胞（hBMSC）的成骨分化 处理成骨细胞祖细胞和成骨细胞并通过传统测定和简单的数字图象分析研究其对成骨细胞行为的影响
生化/生理作用
阿仑膦酸钠三水合物是一种骨吸收抑制剂；法尼基二磷酸合成酶抑制剂 (IC 50 = 460 nM)；CD45 蛋白酪氨酸磷酸酶抑制剂。
阿伦膦酸盐是一种含氮二膦酸盐，可阻断甲羟戊酸途径 并限制破骨功能和活性。阿仑膦酸钠三水合物是一种骨吸收抑制剂、法尼基二磷酸合成酶抑制剂和 CD45 蛋白酪氨酸磷酸酶抑制剂。
储存及稳定性
重溶后，建议在-20°C下分装冻存。储备液在-20°C条件下可稳定保存6个月。
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
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