推荐产品
product name
5-氨基乙酰丙酸盐 盐酸盐, ≥98%
品質等級
化驗
≥98%
形狀
powder
技術
ligand binding assay: suitable
mp
150 °C
儲存溫度
−20°C
SMILES 字串
Cl[H].NCC(=O)CCC(O)=O
InChI
1S/C5H9NO3.ClH/c6-3-4(7)1-2-5(8)9;/h1-3,6H2,(H,8,9);1H
InChI 密鑰
ZLHFONARZHCSET-UHFFFAOYSA-N
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相关类别
應用
5-氨基乙酰丙酸盐酸盐可以用来激活或抑制HeLa和K562细胞系中血红素生物合成。它用于A431肿瘤携带小鼠光动力治疗。
生化/生理作用
5-氨基乙酰丙酸(5-ALA)是血红素生物合成的中间物,可以用于治疗癌症。它是一种非蛋白氨基酸。5-ALA同样用于农业。它可用作基于转移性淋巴结荧光诊断原卟啉 IX (PPIX)抑制剂。5-ALA可以用于疾病光动力诊疗,比如Paget疾病和HPV感染有关的宫颈尖锐湿疣。
血红素生物合成中间体。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
其他客户在看
ALA-PpIX variability quantitatively imaged in A431
epidermoid tumors using in vivo ultrasoundfluorescence
tomography and ex vivo assay
epidermoid tumors using in vivo ultrasoundfluorescence
tomography and ex vivo assay
SPIE Proc., 8931 null
Treatment of HPV infection-associated cervical condylomata acuminata with 5-aminolevulinic acid-mediated photodynamic therapy.
Photochemistry and Photobiology, 88(3), 565-569 (2012)
The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation
The Journal of Clinical Investigation, 122(12), 4569-4579 (2012)
The Journal of surgical research, 176(2), 430-436 (2012-01-10)
Lymph node metastasis is one of the most critical prognostic factors in patients with colorectal cancer. Although regional lymph nodes should be surgically resected and pathologically examined, techniques for the intraoperative diagnosis of lymph node metastasis remain to be well
Structure (London, England : 1993), 26(4), 580-589 (2018-03-20)
5-Aminolevulinic acid synthase (ALAS) catalyzes the first step in heme biosynthesis. We present the crystal structure of a eukaryotic ALAS from Saccharomyces cerevisiae. In this homodimeric structure, one ALAS subunit contains covalently bound cofactor, pyridoxal 5'-phosphate (PLP), whereas the second
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