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Merck

A1765

Sigma-Aldrich

乙酰辅酶A合成酶 来源于面包酵母(酿酒酵母

lyophilized powder, ≥3 units/mg protein

别名:

乙酸硫激酶, 醋酸CoA连接酶(AMP形成)

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About This Item

CAS号:
EC 号:
MDL编号:
UNSPSC代码:
12352204
NACRES:
NA.26

表单

lyophilized powder

质量水平

比活

≥3 units/mg protein

组成

Protein, 10-30% biuret

储存温度

−20°C

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应用

S-乙酰辅酶 A 合成酶可用于研究各种代谢途径,例如糖酵解、糖异生、丙酮酸代谢和 CO2 固定。它也可以用于基因表达研究。
来自面包酵母的 S-乙酰辅酶 A 合成酶已用于合成 5′-磷酸四磷酸腺苷和 5′-磷酸五磷酸腺苷。

生化/生理作用

乙酰辅酶 A 合成酶催化乙酰辅酶 A 的产生。它参与细胞核中的组蛋白乙酰化。它可能参与不可发酵碳源(如甘油)的生长。乙酰辅酶 A 合成酶是由乙酸盐、乙醛和乙醇诱导的

包装

包装尺寸基于蛋白质含量。

单位定义

在 37°C,pH 7.5 下,一个单位每分钟将从乙酸盐、ATP 和辅酶 A 生成 1.0 μ 摩尔 S-乙酰辅酶 A。

外形

冻干粉末,含有稳定剂,如磷酸钾、蔗糖和还原型谷胱甘肽

象形图

Health hazard

警示用语:

Danger

危险声明

预防措施声明

危险分类

Resp. Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Guillaume Baptist et al.
Nucleic acids research, 41(17), e164-e164 (2013-07-31)
We have developed a new screening methodology for identifying all genes that control the expression of a target gene through genetic or metabolic interactions. The screen combines mutant libraries with luciferase reporter constructs, whose expression can be monitored in vivo
Adenosine 5'-tetraphosphate and adenosine 5'-pentaphosphate are synthesized by yeast acetyl coenzyme A synthetase.
Guranowski A, et al.
Journal of Bacteriology, 176(10), 2986-2990 (1994)
Sergio Renilla et al.
Applied microbiology and biotechnology, 93(5), 2109-2124 (2011-09-02)
Impairment of acetate production in Escherichia coli is crucial for the performance of many biotechnological processes. Aerobic production of acetate (or acetate overflow) results from changes in the expression of central metabolism genes. Acetyl-CoA synthetase scavenges extracellular acetate in glucose-limited
Sara Castaño-Cerezo et al.
Molecular microbiology, 82(5), 1110-1128 (2011-11-09)
Lysine acetylation is a well-established post-translational modification widely conserved and distributed in bacteria. Although multiple regulatory roles have been proved, little is known about its regulation. Here, we present evidence that the transcription of the Gcn5-like acetyltransferase YfiQ of Escherichia
Saurabh Sahar et al.
The Journal of biological chemistry, 289(9), 6091-6097 (2014-01-16)
The circadian clock regulates a wide range of physiological and metabolic processes, and its disruption leads to metabolic disorders such as diabetes and obesity. Accumulating evidence reveals that the circadian clock regulates levels of metabolites that, in turn, may regulate

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