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Key Documents

818M-9

Sigma-Aldrich

Cytokeratin 8 & 18 (B22.1 & B23.1) Mouse Monoclonal Antibody

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

mouse

品質等級

100
500

共軛

unconjugated

抗體表格

diluted ascites fluid

抗體產品種類

primary antibodies

無性繁殖

B22.1 & B23.1, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions (See Chart)

形狀

buffered aqueous solution

物種活性

human

包裝

vial of 0.1 mL concentrate (818M-94)
vial of 0.5 mL concentrate (818M-95)
bottle of 1.0 mL predilute (818M-97)
vial of 1.0 mL concentrate (818M-96)
bottle of 7.0 mL predilute (818M-98)

製造商/商標名

Cell Marque

技術

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

同型

IgG1κ

控制

prostate, salivary gland

運輸包裝

wet ice

儲存溫度

2-8°C

視覺化

cytoplasmic

基因資訊

human ... KRT8(3856)

一般說明

Cytokeratins 8 &18 (CK 8 & 18) are major components of the intermediate filaments in the thyroid, liver, and most simple epithelia (e.g. breast, gastrointestinal and respiratory tracts). Anti-CK 8 & 18 is found to stain most adenocarcinomas and squamous cell carcinomas. CK8 & 18 are frequently used as the epithelial markers for identifying Paget cells, metastatic gastric, and colorectal carcinomas.

品質


IVD

IVD

IVD

RUO

聯結

Cytokeratin 8 & 18 Positive Control Slides, Product No. 818S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外觀

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

準備報告

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他說明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律資訊

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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B Angus et al.
The Journal of pathology, 153(4), 377-384 (1987-12-01)
Production of a new monoclonal antibody designated NCL-5D3 is described. The antibody recognizes several low molecular weight cytokeratins, in particular cytokeratin Moll number 8 as determined by immunoblotting studies, and is highly effective for immunocytochemistry using routinely processed paraffin-embedded material.
J M Corson
Pathology annual, 21 Pt 2, 47-81 (1986-01-01)
Keratin protein immunohistochemistry is a powerful diagnostic tool whose role has already been firmly established in many surgical pathology laboratories. Recent studies of the biology of keratin proteins have defined the heterogeneity of keratin protein expression among various epithelial tissues
M Sasaki et al.
Histopathology, 32(3), 199-208 (1998-05-06)
Recent reports suggest that genetic examination of K-ras or p53 mutation is more sensitive for the detection of occult lymph node metastasis in colorectal carcinomas than conventional examination by haematoxylin and eosin (H & E) staining or immunohistochemistry for gene

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