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Merck

61251

Sigma-Aldrich

棕榈酰-L-左旋肉碱

≥97.0% (HPLC)

别名:

(2R)-3-羧基-N,N,N-三甲基-2-[(1-氧代十六烷基)氧基]-1-丙烯胺 内盐, L-肉碱十六烷基酯, C16-左旋肉碱, 十六烷-L-左旋肉碱

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About This Item

经验公式(希尔记法):
C23H45NO4
CAS号:
分子量:
399.61
Beilstein:
4152034
MDL编号:
UNSPSC代码:
12352211
PubChem化学物质编号:
NACRES:
NA.26

质量水平

方案

≥97.0% (HPLC)

旋光性

[α]/D -17±2°, c = 1 in methanol

杂质

≤10% water

储存温度

2-8°C

SMILES字符串

C[N+](C)(C)C[C@H](OC(CCCCCCCCCCCCCCC)=O)CC([O-])=O

InChI

1S/C23H45NO4/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(27)28-21(19-22(25)26)20-24(2,3)4/h21H,5-20H2,1-4H3/t21-/m1/s1

InChI key

XOMRRQXKHMYMOC-OAQYLSRUSA-N

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生化/生理作用

L-棕榈酰肉碱可改变数种酶和转运蛋白的活性,定位于膜中并能在脂肪酸氧化过程中促进长链脂肪酸从细胞质向线粒体中的转移。L-棕榈酰肉碱会在缺血心肌中累积,并可能通过膜分子动力学的改变而导致心肌损伤。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Obesity is currently epidemic in many countries worldwide and is strongly related to diabetes and cardiovascular disease. This study investigated the differences in metabolomic profiling between overweight/obese and normal-weight men. Overweight/obese (n=30) and age-matched, normal-weight men (n=30) were included. Anthropometric
Adolfas Toleikis et al.
Cells, 9(2) (2020-02-07)
Fatty acids are the main respiratory substrates important for cardiac function, and their oxidation is altered during various chronic disorders. We investigated the mechanism of fatty acid-oxidation-induced changes and their relations with mitochondrial morphology and ADP/ATP carrier conformation on the
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Obesity (Silver Spring, Md.), 18(9), 1695-1700 (2010-01-30)
Dysregulation of fatty acid oxidation (FAO) is recognized as important in the pathophysiology of obesity and insulin resistance (IR). However, demonstrating FAO defects in vivo in humans has entailed complex and invasive methodologies. Recently, the identification of genetic blocks in
Margaret-Ann M Nelson et al.
Amino acids, 51(1), 97-102 (2018-09-08)
Oxidative deamination of norepinephrine (NE) and dopamine (DA) by monoamine oxidase (MAO) generates the catecholaldehydes 3,4-dihydroxyphenylglycolaldehyde (DOPEGAL) and 3,4-dihydroxyphenylacetaldehyde (DOPAL), respectively, and H2O2. Catecholaldehydes are highly reactive electrophiles that have been implicated as causal factors in the etiology of neurodegenerative
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Cancer research, 80(6), 1258-1267 (2019-11-27)
Glioblastoma (GBM) is increasingly recognized as a disease involving dysfunctional cellular metabolism. GBMs are known to be complex heterogeneous systems containing multiple distinct cell populations and are supported by an aberrant network of blood vessels. A better understanding of GBM

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