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Merck
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Key Documents

540-05A

Sigma-Aldrich

Human Lung Microvascular Endothelial Cells: HLMVEC, adult

别名:

HLMVEC, HLMVEC cells

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About This Item

分類程式碼代碼:
41106514
NACRES:
NA.81

生物源

human lung (normal)

品質等級

包裝

pkg of 500,000 cells

製造商/商標名

Cell Applications, Inc

增長模式

Adherent

染色體組型

2n = 46

形態學

Endothelial

技術

cell culture | mammalian: suitable

相關疾病

metastasis

運輸包裝

dry ice

儲存溫度

−196°C

一般說明

Lot specific orders are not able to be placed through the web. Contact your local sales rep for more details.

The pulmonary vasculature is of great physiological/pathological significance. It is now recognized to be a tissue composed of metabolically active, functionally responsive cells, that interact with circulating substrates and regulate the composition of systemic arterial blood, affect target organ functions, and contribute to thrombosis, hemostasis and immune reactions, as well as tumor metastasis. Human Lung Microvascular Endothelial Cells (HLMVEC) provide a useful tool for studying various aspects of pathology and biology of the pulmonary microvasculature in vitro.

HLMVEC have been used to elucidate the therapeutic effects of Angiotensin I-converting enzyme (ACE) inhibitors, and the results revealed that they provide an additional benefit to patients by activating bradykinin B1 receptor leading to prolonged nitric oxide (NO) production in endothelial cells and inhibition of PKCε (Ignjatovic, 2004; Stanisavljevic, 2006).

細胞系來源

Lungs

應用

lung physiology, metabolism, regulate blood composition, hemostasis, immune reactions, therapeutic effects, leukocyte migration,

成分

Cell Basal Medium containing 10% FBS & 10% DMSO

準備報告

  • 3rd passage, >500,000 cells in Cell Basal Medium containing 10% FBS & 10% DMSO
  • Can be cultured at least 15 doublings

例行更新培養

Please refer to the HLMVEC Culture Protocol.

免責聲明

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Huiyuan Yan et al.
Experimental and therapeutic medicine, 26(1), 319-319 (2023-06-05)
Acute lung injury (ALI) is associated with increased lung inflammation and lung permeability. The present study aimed to determine the role of inactive rhomboid-like protein 2 (iRHOM2) in ALI in lipopolysaccharide (LPS)-induced pulmonary microvascular endothelial cell model. Human pulmonary microvascular

实验方案

Technical information for working with human lung microvascular endothelial cells including thawing, subculturing and cryopreservation

Technical information for working with human lung microvascular endothelial cells including thawing, subculturing and cryopreservation

Technical information for working with human lung microvascular endothelial cells including thawing, subculturing and cryopreservation

Technical information for working with human lung microvascular endothelial cells including thawing, subculturing and cryopreservation

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