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Merck

46985

Sigma-Aldrich

荧光素-5-氨基硫脲

suitable for fluorescence, ~80% (HPCE)

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About This Item

经验公式(希尔记法):
C21H15N3O5S
CAS号:
分子量:
421.43
MDL號碼:
分類程式碼代碼:
12352125
PubChem物質ID:
NACRES:
NA.32

化驗

~80% (HPCE)

品質等級

形狀

solid

溶解度

DMF: soluble
H2O: soluble

螢光

λex 492 nm; λem 516 nm in 0.1 M Tris pH 9.0

適合性

suitable for fluorescence

儲存溫度

−20°C

SMILES 字串

NNC(=S)Nc1ccc(c(c1)C(O)=O)C2=C3C=CC(=O)C=C3Oc4cc(O)ccc24

InChI

1S/C21H15N3O5S/c22-24-21(30)23-10-1-4-13(16(7-10)20(27)28)19-14-5-2-11(25)8-17(14)29-18-9-12(26)3-6-15(18)19/h1-9,25H,22H2,(H,27,28)(H2,23,24,30)

InChI 密鑰

MEUCHQDLZYLNQY-UHFFFAOYSA-N

相关类别

一般說明

荧光素-5-氨基硫脲,也称为 FTC,是一种荧光探针。FTSC 荧光光谱类似于 FITC,这是蛋白质组学的优选荧光标签。 通过还原胺化获得的 FTSC 标记囊泡的荧光光谱特性与荧光仪器的氩激光完全兼容。

應用

荧光素-5- 氨基硫脲可用作荧光标记试剂,以标记:
  • 细胞表面官能团(血型糖蛋白),以研究红细胞膜脱氧的影响。
  • 适用于活细胞多糖成像的糖类。
  • 适用于细胞特异性给药应用中的硫酸软骨素纳米凝胶。

特點和優勢

荧光素-5-氨基硫脲具有以下优点-

  • 它显示出强烈的荧光特性。
  • 显示了氨基硫脲基团对醛基的固有反应性。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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J D Corbett et al.
Biophysical journal, 66(1), 25-30 (1994-01-01)
We have used the fluorescence photobleaching recovery technique to study the dependence on oxygen tension of the lateral mobility of fluorescently labeled band 3, the phospholipid analogue fluorescein phosphatidylethanolamine, and glycophorins in normal red blood cell membranes. Band 3 protein
Hua Tian et al.
Journal of cellular and molecular medicine, 21(1), 107-120 (2016-08-12)
Oxidative stress and inflammation play important roles in the pathogenesis of cardiovascular disease (CVD). Oxidative stress-induced desialylation is considered to be a primary step in atherogenic modification, and therefore, the attenuation of oxidative stress and/or inflammatory reactions may ameliorate CVD.
Deoxygenation affects fluorescence photobleaching recovery measurements of red cell membrane protein lateral mobility
Corbett JD, et al.
Biophysical Journal, 66(1), 25-30 (1994)
Injectable hydrogel-incorporated cancer cell-specific cisplatin releasing nanogels for targeted drug delivery
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Yun Bai et al.
Nucleic acids research, 41(16), 7861-7874 (2013-06-21)
The 3' untranslated region (3'UTR) of hepatitis C virus (HCV) messenger RNA stimulates viral translation by an undetermined mechanism. We identified a high affinity interaction, conserved among different HCV genotypes, between the HCV 3'UTR and the host ribosome. The 3'UTR

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