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Merck
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主要文件

275R-1

Sigma-Aldrich

Ki-67 (SP6) Rabbit Monoclonal Antibody

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

100
500

偶联物

unconjugated

抗体形式

culture supernatant

抗体产品类型

primary antibodies

克隆

SP6, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions (See Chart)

表单

buffered aqueous solution

种属反应性

human

包装

vial of 0.1 mL concentrate (275R-14)
vial of 0.5 mL concentrate (275R-15)
bottle of 1.0 mL predilute (275R-17)
vial of 1.0 mL concentrate (275R-16)
bottle of 7.0 mL predilute (275R-18)

制造商/商品名称

Cell Marque®

技术

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

同位素/亚型

IgG

控制

tonsil

运输

wet ice

储存温度

2-8°C

可视化

nuclear

基因信息

human ... MKI67(4288)

一般描述

The Ki-67 antigen is a nuclear, non-histone protein that is present in proliferatingcells. Though its specific role is largely postulated and still yet to be determined,Ki-67’s presence during cellular division makes it an excellent target for labeling rapidlygrowing malignancies. Given that its presence correlates with cell proliferation, theimmunohistochemical labeling of Ki-67 antigen may be useful in characterizing a lesion’sgrowth fraction.

质量


IVD

IVD

IVD

RUO

联系

Ki-67 Positive Control Slides, Product No. 275S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

制备说明

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他说明

For Technical Service please contact: 800-665-7284 or email: [email protected]

法律信息

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Swerdlow S, et al. WHO clarifications of tumours of hematopoietic and lymphoid tissues. 4th edition, 2008. P 220.
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissue, 220-220 (2008)
S W Coons et al.
Neurosurgery, 41(4), 878-884 (1997-10-08)
The prognostic significance of quantitative measurement of tumor proliferative activity was evaluated for oligodendroglial tumors. Ki-67/MIB-1 immunochemistry was used to measure proliferative activity in 81 oligodendrogliomas and oligoastrocytomas. The relationship among survival, proliferation, histological features, and clinical variables were evaluated
Ran Marciano et al.
Cancers, 11(2) (2019-02-02)
Tumor cells utilize glucose to fuel their anabolic needs, including rapid proliferation. However, due to defective vasculature and increased glucose uptake, tumor cells must overcome glucose deprivation. Accordingly, tumor cells depend on cellular pathways promoting survival under such conditions. Targeting
Nirmala Pathmanathan et al.
Journal of clinical pathology, 66(6), 512-516 (2013-02-26)
New approaches to the prognostic assessment of breast cancer have come from molecular profiling studies. A major feature of this work has been to emphasise the importance of cancer cell proliferation as a key discriminative indicator of recurrence risk for
P E McKeever et al.
Journal of neuropathology and experimental neurology, 57(10), 931-936 (1998-10-24)
The purpose of this study was to determine whether a relationship existed between MIB-1 labeling index (LI) percentages and survival in patients with grade II astrocytomas. From archival paraffin-embedded surgical specimens of 50 patients of the University of Michigan Medical

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