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Merck

14300

Sigma-Aldrich

甜菜碱 一水合物

≥99.0% (NT)

别名:

1-carboxy-n,n,n-trimethylmethanaminium hydroxide, 2-(trimethylammonio)acetate hydrate, glycine betaine hydrate

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About This Item

线性分子式:
(CH3)3N+CH2COO- · H2O
CAS号:
分子量:
135.16
Beilstein:
3626258
EC號碼:
MDL號碼:
分類程式碼代碼:
51171529
PubChem物質ID:
NACRES:
NA.25

化驗

≥99.0% (NT)

形狀

solid

溶解度

H2O: 0.1 g/mL, clear, colorless

儲存溫度

2-8°C

SMILES 字串

O.C[N+](C)(C)CC([O-])=O

InChI

1S/C5H11NO2.H2O/c1-6(2,3)4-5(7)8;/h4H2,1-3H3;1H2

InChI 密鑰

NJZRLXNBGZBREL-UHFFFAOYSA-N

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應用

甜菜碱一水合物:

  • 适用于通过减少由富含GC的区域引起的二级结构的形成来提高富含GC的DNA序列的PCR扩增
  • 适用于作为PCR反应混合物的组分
  • 适用于鉴定PCR产量增强剂的研究
  • 已经用于研究饲喂缺乏甲硫氨酸和低相容渗透物质的日粮的仔猪的氮平衡和养分消化率
  • 还用于比较压力对三层水合物的影响

生化/生理作用

胆碱氧化代谢的终产物,甜菜碱是一个普遍的甲基供体,特别是在蛋氨酸生物合成的次要途径。用于治疗蛋氨酸生物合成主要途径缺陷的同型胱氨酸尿症。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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M Kovárová et al.
Nucleic acids research, 28(13), E70-E70 (2000-06-28)
Tetramethylammonium (TMA) chloride, dimethyl sulfoxide and formamide are known to increase, under certain conditions, the specificity and efficiency of the polymerase chain reaction (PCR). We compared the ability of several TMA derivatives and some other reagents to increase the specificity
Theodore Spilker et al.
Journal of clinical microbiology, 50(9), 3010-3015 (2012-07-13)
The genus Achromobacter currently is comprised of seven species, including Achromobacter xylosoxidans, an opportunistic and nosocomial pathogen that displays broad-spectrum antimicrobial resistance and is recognized as causing chronic respiratory tract infection in persons with cystic fibrosis (CF). To enable strain
Meike Eklund et al.
Archives of animal nutrition, 60(4), 289-300 (2006-08-23)
A balance experiment was carried out to investigate the effects of betaine monohydrate (BET) or betaine derived from condensed molasses solubles (CMS) as a substitute for methionine and choline on nitrogen (N) balance and total tract nutrient digestibility in weaned
Russell D L Johnstone et al.
Acta crystallographica. Section B, Structural science, 65(Pt 6), 731-748 (2009-11-20)
We report the effect of pressure on the crystal structures of betaine monohydrate (BTM), L-cysteic acid monohydrate (CAM) and S-4-sulfo-L-phenylalanine monohydrate (SPM). All three structures are composed of layers of zwitterionic molecules separated by layers of water molecules. In BTM
W Henke et al.
Nucleic acids research, 25(19), 3957-3958 (1997-10-10)
Betaine improves the co-amplification of the two alternatively spliced variants of the prostate-specific membrane antigen mRNA as well as the amplification of the coding cDNA region of c-jun. It is suggested that betaine improves the amplification of these genes by

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