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Merck

SMB00972

Sigma-Aldrich

Potassium phenyl sulfate

别名:

Phenyl potassium sulfate

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About This Item

经验公式(希尔记法):
C6H5KO4S
CAS号:
分子量:
212.26
MDL號碼:
NACRES:
NA.21

化驗

≥98% (HPLC)

品質等級

形狀

solid

溶解度

water: soluble

儲存溫度

2-8°C

InChI

1S/C6H6O4S.K/c7-11(8,9)10-6-4-2-1-3-5-6;/h1-5H,(H,7,8,9);/q;+1/p-1

InChI 密鑰

NOUFXYHWAWIDNT-UHFFFAOYSA-M

一般說明

Potassium phenyl sulfate is the salt of gut metabolite phenol sulfate.It is biosynthesized from phenol and phosphoadenosine phosphosulfate through the action of the enzyme sulfotransferase 1A1 in the liver. Also, it induces reactive oxygen species (ROS) production and decreases glutathione levels, rendering cells vulnerable to oxidative stress.

應用

Metabolomics research
Microbiome research

其他說明

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儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Takeo Edamatsu et al.
PloS one, 13(2), e0193342-e0193342 (2018-02-24)
In chronic kidney disease patients, oxidative stress is generally associated with disease progression and pathogenesis of its comorbidities. Phenyl sulfate is a protein-bound uremic solute, which accumulates in chronic kidney disease patients, but little is known about its nature. Although
Koichi Kikuchi et al.
Nature communications, 10(1), 1835-1835 (2019-04-25)
Diabetic kidney disease is a major cause of renal failure that urgently necessitates a breakthrough in disease management. Here we show using untargeted metabolomics that levels of phenyl sulfate, a gut microbiota-derived metabolite, increase with the progression of diabetes in

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