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文件

PHR2099

头孢噻肟钠

Name: 头孢噻肟钠
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

Cefotaxime sodium salt 钠盐, Cefotaxim sodium salt 钠盐

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About This Item

经验公式（希尔记法）:

C₁₆H₁₆N₅NaO₇S₂

CAS号:

64485-93-4

分子量:

477.45

Beilstein:

5711411

MDL號碼:

MFCD00079073

分類程式碼代碼:

41116107

NACRES:

NA.24

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C0685000

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等級

certified reference material
pharmaceutical secondary standard

品質等級

300

agency

traceable to Ph. Eur. C0685000
traceable to USP 1097909

API 家族

cefotaxime

形狀

powder

CofA

current certificate can be downloaded

包裝

pkg of 1 g

應用

pharmaceutical small molecule

儲存溫度

2-8°C

SMILES 字串

[Na+].[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c3csc(N)n3)C([O-])=O

InChI

1S/C16H17N5O7S2.Na/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8;/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26);/q;+1/p-1/b20-9-;/t10-,14-;/m1./s1

InChI 密鑰

AZZMGZXNTDTSME-JUZDKLSSSA-M

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一般說明

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

應用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化／生理作用

Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.

其他說明

Broad spectrum third generation cephalosporin antibiotic.

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

分析報告

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

腳註

To see an example of a Certificate of Analysis for this material enter LRAB9060 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.