PHR1975

右美沙芬杂质C

Pharmaceutical Secondary Standard; Certified Reference Material

• 别名: (9α,13α,14α)-3-Methoxy-17-methylmorphinan-10-one, 10-Keto dextromethorphan
• 经验公式（希尔记法）: C₁₈H₂₃NO₂
• CAS号: 57969-05-8
• 分子量: 285.38
• 分類程式碼代碼: 41116107
• NACRES: NA.24

属性

• 等級: certified reference material; pharmaceutical secondary standard
• 品質等級: 300
• agency: traceable to USP 1181040
• CofA: current certificate can be downloaded
• 包裝: pkg of 30 mg
• 應用: pharmaceutical
• 格式: neat
• 儲存溫度: 2-30°C
• InChI: 1S/C18H23NO2/c1-19-10-9-18-8-4-3-5-14(18)16(19)17(20)13-7-6-12(21-2)11-15(13)18/h6-7,11,14,16H,3-5,8-10H2,1-2H3/t14-,16-,18+/m1/s1
• InChI 密鑰: UOCRGKKCNCIQCZ-KYJSFNMBSA-N

说明

一般說明

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

應用

• Pharmacokinetic Study of Alpha-Hydroxytriazolam: Research involving the urinary excretion of alpha-hydroxytriazolam after a single dose of Halcion provides insights into the metabolic pathways and elimination characteristics of this benzodiazepine derivative. Using α-Hydroxytriazolam-d₄ as an internal standard in mass spectrometry enhances the accuracy of such studies, which is critical for understanding the drug′s behavior in the human body and for developing therapeutic guidelines (Lin et al., 2005).


• Confirmation of Urinary Benzodiazepine Metabolites: A study that utilizes gas chromatography-mass spectrometry (GC-MS) to confirm the presence of urinary benzodiazepine metabolites, including α-Hydroxytriazolam, emphasizes the role of α-Hydroxytriazolam-d₄ as a vital analytical standard. This research aids in forensic toxicology and clinical diagnostics by providing robust methodologies for the detection and quantification of benzodiazepines in biological samples (Meatherall, 1994).

分析報告

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAB3994 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

安全信息

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H301,H336
• 防範說明: P261 - P264 - P270 - P271 - P301 + P310 - P304 + P340 + P312
• 危險分類: Acute Tox. 3 Oral - STOT SE 3
• 標靶器官: Central nervous system
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable