PHR1955

盐酸甲哌卡因

Pharmaceutical Secondary Standard; Certified Reference Material

• 别名: Mepivacaine hydrochloride, 1-Methyl-2′,6′-pipecoloxylidine hydrochloride, N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide hydrochloride
• 经验公式（希尔记法）: C₁₅H₂₂N₂O · HCl
• CAS号: 1722-62-9
• 分子量: 282.81
• EC號碼: 217-023-9
• MDL號碼: MFCD00144738
• 分類程式碼代碼: 41116107
• NACRES: NA.24

属性

• 等級: certified reference material; pharmaceutical secondary standard
• 品質等級: 300
• agency: traceable to BP 699; traceable to Ph. Eur. M0370000; traceable to USP 1387002
• API 家族: mepivacaine
• CofA: current certificate can be downloaded
• 包裝: pkg of 500 mg
• 應用: pharmaceutical
• 格式: neat
• 儲存溫度: 2-30°C
• SMILES 字串: CN1CCCCC1C(NC2=C(C)C=CC=C2C)=O.Cl
• InChI: 1S/C15H22N2O.ClH/c1-11-7-6-8-12(2)14(11)16-15(18)13-9-4-5-10-17(13)3;/h6-8,13H,4-5,9-10H2,1-3H3,(H,16,18);1H
• InChI 密鑰: RETIMRUQNCDCQB-UHFFFAOYSA-N
• 基因資訊: human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

说明

一般說明

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Mepivacaine hydrochloride is a local anesthetic that is related chemically and pharmacologically to the amide-type local anesthetics. It is often administered via local infiltration, peripheral nerve block, etc.

應用

Mepivacaine hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化／生理作用

Local anesthetic. Reversibly blocks transient Na⁺ inward current, as well as the steady-state K⁺ outward current. Blocks tandem pore (TASK) and Kv1.5, potassium channels in model systems.

分析報告

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAB1955 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

安全信息

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H301,H336
• 防範說明: P261 - P264 - P270 - P271 - P301 + P310 - P304 + P340 + P312
• 危險分類: Acute Tox. 3 Oral - STOT SE 3
• 標靶器官: Central nervous system
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable