PHR1682

巴氯芬

Pharmaceutical Secondary Standard; Certified Reference Material

• 别名: (±)-巴氯芬, (±)-β-（氨甲基）-4-氯苯丙酸, 巴氯芬片
• 经验公式（希尔记法）: C₁₀H₁₂ClNO₂
• CAS号: 1134-47-0
• 分子量: 213.66
• EC號碼: 214-486-9
• MDL號碼: MFCD00055143
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329823553
• NACRES: NA.24

属性

• 等級: certified reference material; pharmaceutical secondary standard
• 品質等級: 300
• agency: traceable to BP 28; traceable to Ph. Eur. B0200000; traceable to USP 1048200
• API 家族: baclofen
• CofA: current certificate can be downloaded
• 包裝: pkg of 1 g
• 技術: HPLC: suitable; gas chromatography (GC): suitable
• 應用: pharmaceutical (small molecule)
• 格式: neat
• 儲存溫度: 2-30°C
• SMILES 字串: ClC1=CC=C(C(CN)CC(O)=O)C=C1
• InChI: 1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)
• InChI 密鑰: KPYSYYIEGFHWSV-UHFFFAOYSA-N
• 基因資訊: human ... GABBR1(2550) , GABBR2(9568)

说明

一般說明

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Baclofen is a structural analog of γ-aminobutyric acid (GABA) and an antispastic agent commonly used for the treatment of spasticity as a result of spinal cord or brain injury.

應用

Baclofen may be used as a pharmaceutical secondary reference standard for the determination of the analyte in plasma samples by liquid chromatography tandem mass spectrometry and tablet formulations by UV spectroscopy, respectively.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化／生理作用

GABA _B 受体激动剂；骨骼肌松弛剂；解痉剂。

分析報告

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAA6298 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

推薦產品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

安全信息

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H301
• 防範說明: P264 - P270 - P301 + P310 - P405 - P501
• 危險分類: Acute Tox. 3 Oral
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable