所有图片(3)
About This Item
经验公式（希尔记法）:
C15H13N3O4S
CAS号:
分子量:
331.35
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.77
推荐产品
生物源
synthetic (organic)
品質等級
化驗
≥98% (TLC)
形狀
powder
儲存溫度
2-8°C
SMILES 字串
CN1C(C(=O)Nc2ccccn2)=C(O)c3ccccc3S1(=O)=O
InChI
1S/C15H13N3O4S/c1-18-13(15(20)17-12-8-4-5-9-16-12)14(19)10-6-2-3-7-11(10)23(18,21)22/h2-9,19H,1H3,(H,16,17,20)
InChI 密鑰
QYSPLQLAKJAUJT-UHFFFAOYSA-N
基因資訊
human ... PTGS1(5742) , PTGS2(5743)
rat ... Alox5(25290)
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應用
吡罗昔康已用于：
- 诱发小鼠结肠炎
- 作为非类固醇抗炎药，提高白介素-10(IL-10)敲除小鼠对肠道损伤的敏感性
- 研究其作为化学预防试剂和阳性对照，对小鼠小肠肿瘤生长的影响
生化／生理作用
吡罗昔康(Piroxicam)是非类固醇抗炎药(NSAID)。具有镇痛活性，对风湿病有治疗作用。
环加氧酶抑制剂。
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 3 Oral - STOT RE 2 Oral
標靶器官
Gastrointestinal tract
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
从最新的版本中选择一种：
分析证书(COA)
Lot/Batch Number
其他客户在看
Thymoquinone attenuates tumor growth in ApcMin mice by interference with Wnt-signaling
Lang M, et al.
Molecular Cancer, 12(1), 41-41 (2013)
Jiawei Guo et al.
Cell reports. Medicine, 4(1), 100881-100881 (2023-01-06)
Systematic bone loss is commonly complicated with inflammatory bowel diseases (IBDs) with unclear pathogenesis and uncertain treatment. In experimental colitis mouse models established by dextran sulfate sodium and IL-10 knockout induced with piroxicam, bone mass and quality are significantly decreased.
Piroxicam, a potent inhibitor of prostaglandin production in cell culture. Structure-activity study.
T J Carty et al.
Prostaglandins, 19(1), 51-59 (1980-01-01)
The new non-steroidal antiinflammatory (NSAI)2 agent, piroxicam [4-hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide], is a highly active inhibitor of prostaglandin (PG) synthesis by methylcholanthrene transformed mouse fibroblasts (MC5-5) and rabbit synovial cells in culture. Comparison of the PG biosynthesis inhibitory activity of piroxicam with
Michaela Lang et al.
Molecular cancer, 12(1), 41-41 (2013-05-15)
Patients with familial adenomatous polyposis (FAP) are at increased risk for the development of colorectal cancer. Surgery and chemoprevention are the most effective means to prevent cancer development. Thymoquinone (TQ) is considered the main compound of the volatile Nigella sativa
Seung-Won Choi et al.
Plant biotechnology (Tokyo, Japan), 39(3), 323-327 (2022-11-10)
Agrobacterium-mediated transformation is a key innovation for plant breeding, and routinely used in basic researches and applied biology. However, the transformation efficiency is often the limiting factor of this technique. In this study, we discovered that oxicam-type nonsteroidal anti-inflammatory drugs
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