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Merck

E3768

Sigma-Aldrich

(-)-表没食子儿茶素

≥95% (HPLC), from green tea

别名:

(-)--2-(3,4,5-三羟基苯基)-3,4-二氢-1 (2 H )-苯并吡喃-3,5,7-三醇, (-)-cis-3,3′,4′,5,5′,7-Hexahydroxyflavane

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About This Item

经验公式(希尔记法):
C15H14O7
CAS号:
分子量:
306.27
MDL號碼:
分類程式碼代碼:
12352205
PubChem物質ID:
NACRES:
NA.21

生物源

green tea

品質等級

化驗

≥95% (HPLC)

應用

metabolomics
vitamins, nutraceuticals, and natural products

儲存溫度

2-8°C

SMILES 字串

O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3cc(O)c(O)c(O)c3

InChI

1S/C15H14O7/c16-7-3-9(17)8-5-12(20)15(22-13(8)4-7)6-1-10(18)14(21)11(19)2-6/h1-4,12,15-21H,5H2/t12-,15-/m1/s1

InChI 密鑰

XMOCLSLCDHWDHP-IUODEOHRSA-N

基因資訊

human ... CYP1A2(1544)

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一般說明

(−)-表没食子儿茶素是绿茶中最主要的儿茶素成分之一,也是含量最丰富(~20%)的一种,具有抗氧化特性。

應用

(−)-表没食子儿茶素(EGC)已用于:
  • 作为高效液相色谱(HPLC)分析的参考标准品
  • 分析其对α-淀粉酶和α-葡糖苷酶的抑制作用,以便控制糖尿病的餐后高血糖
  • 在细胞活力检测中检查其对鼠类胰腺β-细胞的抗铁死亡和铁毒性的保护作用
  • 评估其对长期急性和慢性降植烷诱导关节炎的潜在抗炎影响
  • 处理怀孕和哺乳小鼠,研究其对体外血管生成、增殖和内皮细胞迁移的影响
  • 根据CD4+(分化簇4)和CD8+(分化簇8)细胞数量,评估其对怀孕和哺乳小鼠脾脏的影响

生化/生理作用

(−)-表没食子儿茶素(EGC)已证明可用作抗癌剂,对人乳腺癌细胞MCF-7中heregulin-b1(HRG)诱导的迁移/侵袭具有抑制作用。它也对单纯疱疹病毒具有强抗病毒活性。
绿茶多酚。抗癌剂。抗氧化活性低于 EGCG。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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商品

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

抗氧化剂可保护生物系统免受含氧自由基和氧化还原过渡金属离子(如铁、铜和镉)引起的氧化损伤。

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