所有图片(1)
About This Item
经验公式（希尔记法）:
C26H28N2
CAS号:
分子量:
368.51
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24
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等級
pharmaceutical primary standard
API 家族
cinnarizine
製造商／商標名
EDQM
應用
pharmaceutical (small molecule)
形式
neat
SMILES 字串
C1CN(CCN1C\C=C\c2ccccc2)C(c3ccccc3)c4ccccc4
InChI
1S/C26H28N2/c1-4-11-23(12-5-1)13-10-18-27-19-21-28(22-20-27)26(24-14-6-2-7-15-24)25-16-8-3-9-17-25/h1-17,26H,18-22H2/b13-10+
InChI 密鑰
DERZBLKQOCDDDZ-JLHYYAGUSA-N
基因資訊
human ... CACNA1C(775) , CACNA1D(776) , CACNA1F(778) , CACNA1S(779) , HRH1(3269)
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相关类别
一般說明
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
應用
Cinnarizine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
包裝
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
其他說明
Sales restrictions may apply.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Jed Zaretzki et al.
Bioinformatics (Oxford, England), 29(4), 497-498 (2012-12-18)
Regioselectivity-WebPredictor (RS-WebPredictor) is a server that predicts isozyme-specific cytochrome P450 (CYP)-mediated sites of metabolism (SOMs) on drug-like molecules. Predictions may be made for the promiscuous 2C9, 2D6 and 3A4 CYP isozymes, as well as CYPs 1A2, 2A6, 2B6, 2C8, 2C19
Pieterjan Kayaert et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 81(3), 650-656 (2012-05-15)
One of the benefits of nanocrystals is their positive effect on the solubility and dissolution rate without alterations to the solid state. Up to now, amorphization of nanocrystals after milling or drying has only rarely been described. The results we
Pieterjan Kayaert et al.
The Journal of pharmacy and pharmacology, 63(11), 1446-1453 (2011-10-13)
In this article the feasibility of fluidized bed bead coating of nanosuspensions of drugs with significantly different physicochemical properties was investigated as a process to transform nanosuspensions into a solid dosage form. The second aim was to see how those
Amnon Gil et al.
Clinical neuropharmacology, 35(1), 37-39 (2011-12-06)
The objective of the study was to compare the efficacy of transdermal scopolamine and cinnarizine in the prevention of seasickness and their adverse reactions. Seventy-six naval crew members participated in a double-blind, randomized, crossover study. On 2 voyages, they were
Mohamed A Alhnan et al.
International journal of pharmaceutics, 416(1), 55-60 (2011-06-18)
Poorly water soluble basic drugs are very sensitive to pH changes and following dissolution in the acidic stomach environment tend to precipitate upon gastric emptying, which leads to compromised or erratic oral bioavailability. In this work, we show that the
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