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Merck

B12695

Sigma-Aldrich

苯甲酰氯

ReagentPlus®, ≥99%

别名:

Benzoic acid chloride, alpha-chlorobenzaldehyde

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About This Item

线性分子式:
C6H5COCl
CAS号:
分子量:
140.57
Beilstein:
471389
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.21
价格与库存信息目前不能提供

蒸汽密度

4.88 (vs air)

质量水平

蒸汽压

1 mmHg ( 32 °C)

产品线

ReagentPlus®

方案

≥99%

表单

liquid

自燃温度

1056 °F

expl. lim.

4.9 %

折射率

n20/D 1.553 (lit.)

沸点

198 °C (lit.)

mp

−1 °C (lit.)

密度

1.211 g/mL at 25 °C (lit.)

官能团

acyl chloride
phenyl

SMILES字符串

ClC(=O)c1ccccc1

InChI

1S/C7H5ClO/c8-7(9)6-4-2-1-3-5-6/h1-5H

InChI key

PASDCCFISLVPSO-UHFFFAOYSA-N

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一般描述

苯甲酰氯是一种酰氯,常用作苯甲酰化剂。[1]已有研究报道在钯催化剂存在下,使用苯甲酰氯芳基化1,1-和1,2-二取代的活化烯烃。[2]

应用

苯甲酰氯可用于合成:
  • 在通过K-10粘土支持的铯取代的十二碳磷酸(Cs2.5H0.5PW12O40)存在下,通过苯甲醚的酰化反应得到4-甲氧基二苯甲酮。[3]
  • 在二异丙基乙胺存在下,通过酰化氨基酸得到苯甲酰氨基酸。[4]
  • 在Al促进的硫酸化氧化锆催化剂存在下,可通过甲苯苯甲酰化,制备p-,o-,m-甲基二苯甲酮。[5]

法律信息

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Skull and crossbonesCorrosion

警示用语:

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

闪点(°F)

161.6 °F - closed cup

闪点(°C)

72 °C - closed cup

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Benzoylation of anisole over borate zirconia solid acid catalyst.
Patil PT, et al.
Catalysis Communications, 3(9), 411-416 (2002)
Stereochemical course of the palladium-catalysed arylation of disubstituted activated alkenes with benzoyl chloride.
Spencer A.
Journal of Organometallic Chemistry, 240(2), 209-216 (1982)
Benzoylation of toluene with benzoyl chloride on Al-promoted sulfated solid superacids.
Xia Y, et al.
Catalysis Letters, 55(2), 105-112 (1998)
Nils C Gassen et al.
Nature communications, 12(1), 3818-3818 (2021-06-23)
Viruses manipulate cellular metabolism and macromolecule recycling processes like autophagy. Dysregulated metabolism might lead to excessive inflammatory and autoimmune responses as observed in severe and long COVID-19 patients. Here we show that SARS-CoV-2 modulates cellular metabolism and reduces autophagy. Accordingly
Cesium-substituted dodecatungstophosphoric acid on K-10 clay for benzoylation of anisole with benzoyl chloride.
Yadav GD, et al.
J. Catal., 217(1), 88-99 (2003)

Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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