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Merck

81942

Sigma-Aldrich

丙酸酐

purum, ≥96.0% (NT)

别名:

初油酸酐

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About This Item

线性分子式:
(CH3CH2CO)2O
CAS号:
分子量:
130.14
Beilstein:
507066
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

蒸汽密度

4.5 (vs air)

质量水平

蒸汽压

10 mmHg ( 57.7 °C)

等级

purum

方案

≥96.0% (NT)

表单

liquid

自燃温度

545 °F

expl. lim.

11.9 %

折射率

n20/D 1.404 (lit.)
n20/D 1.404

沸点

167 °C (lit.)

mp

−43 °C (lit.)

溶解性

H2O: decomposes (when in contact with water)

密度

1.010 g/mL at 20 °C
1.015 g/mL at 25 °C (lit.)

官能团

anhydride
ester

SMILES字符串

CCC(=O)OC(=O)CC

InChI

1S/C6H10O3/c1-3-5(7)9-6(8)4-2/h3-4H2,1-2H3

InChI key

WYVAMUWZEOHJOQ-UHFFFAOYSA-N

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应用

Propionic anhydride can be used:
  • As an esterifying reagent in the modification of cassava starch by acylation reaction.
  • As a reactant along with anisole in the synthesis of 4-methoxypropiophenone using various solid acid catalysts via Friedel−Crafts acylation reaction.
  • As a reagent in the synthesis of cyanohydrin esters by treating KCN with aldehyde in presence of bimetallic titanium(salen) complex catalyst.

其他说明

可能实行销售限制

象形图

Corrosion

警示用语:

Danger

危险声明

危险分类

Eye Dam. 1 - Skin Corr. 1B

储存分类代码

8A - Combustible corrosive hazardous materials

WGK

WGK 1

闪点(°F)

165.2 °F - closed cup

闪点(°C)

74 °C - closed cup

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Modification of cassava starch by using propionic anhydride and properties of the starch-blended polyester polyurethane
Santayanon R and Wootthikanokkhan J
Carbohydrate Polymers, 51(1), 17-24 (2003)
Synthetic and mechanistic studies on asymmetric cyanohydrin synthesis using a titanium (salen) bimetallic catalyst
Belokon YN, et al.
Tetrahedron, 60(46), 10433-10447 (2004)
Dimensional stabilisation and strength of particleboard by chemical modification with propionic anhydride.
Papadopoulos AN & Gkaraveli A
European Journal of Wood and Wood Products, 61(2), 142-144 (2003)
Hyung Wook Nam et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 826(1-2), 91-107 (2005-09-17)
N-Terminal isotope tagging (NIT) is an important proteomic tool for quantifying proteins in complex mixtures. Here we describe a modified version of the isotope-coded propionylation procedure of Zhang et al. [Zhang et al., Rapid Commun. Mass Spectom. 16 (2002) 2325]
Haim Tsubery et al.
The Journal of biological chemistry, 279(37), 38118-38124 (2004-06-11)
Polyethylene glycol (PEG)-conjugated therapeutic peptides/proteins have been shown to exhibit clinical properties superior to those of their corresponding unmodified parent molecules. However, the desirable pharmacological features gained by protein PEGylation become irrelevant if conjugates are inactivated or cannot reach their

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